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Long-term stability of ganciclovir in polypropylene containers at room temperature.

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

Guichard N, Bonnabry P, Rudaz S, Fleury-Souverain S.
PMID: 28975863
J Oncol Pharm Pract. 2017 Jan 01;1078155217732629. doi: 10.1177/1078155217732629. Epub 2017 Jan 01.

Purpose Ganciclovir is increasingly provided by hospital pharmacy production unit in a ready-to-use form, in order to improve the safety of healthcare workers and the efficiency of the organisation. The objective of this study was to develop a stability-indicating...

Repurposing Drugs in Oncology (ReDO)-clarithromycin as an anti-cancer agent.


Van Nuffel AM, Sukhatme V, Pantziarka P, Meheus L, Sukhatme VP, Bouche G.
PMID: 25729426
Ecancermedicalscience. 2015 Feb 24;9:513. doi: 10.3332/ecancer.2015.513. eCollection 2015.

Clarithromycin (CAM) is a well-known macrolide antibiotic available as a generic drug. CAM is traditionally used for many types of bacterial infections, treatment of Lyme disease and eradication of gastric infection with Helicobacter pylori. Extensive preclinical and clinical data...

Improved pharmacy department workflow with new method of order entry for single-agent, high-dose methotrexate.

Hospital pharmacy

Kintzel PE, VanDyke TH, Athmann PW, Mills LB, Bonter MP, Bremer MW, Dougherty ML, Foster RW, Knight SK, Slot MG, Steinmetz-Malato LL.
PMID: 25673893
Hosp Pharm. 2014 Dec;49(11):1039-43. doi: 10.1310/hjp4911-1039.

PURPOSE: To determine whether a process change impacted the proportion of orders for single-agent, high-dose methotrexate entered by chemotherapy pharmacists instead of general pharmacy staff. Coordination of antiemetic premedication and leucovorin rescue with the new method of order entry...

Identification and cost of adverse events in metastatic breast cancer in taxane and capecitabine based regimens.


Hansen RN, Ramsey SD, Lalla D, Masaquel A, Kamath T, Brammer M, Hurvitz SA, Sullivan SD.
PMID: 24926422
Springerplus. 2014 May 21;3:259. doi: 10.1186/2193-1801-3-259. eCollection 2014.

PURPOSE: We sought to compare the economic impact of treatment-related adverse events (AEs) in patients with metastatic breast cancer (mBC) using taxane- or capecitabine-based treatment regimens as either first- or second-line (FL or SL) therapy in the US.METHODS: We...

Dimethoxycurcumin, a structural analogue of curcumin, induces apoptosis in human renal carcinoma caki cells through the production of reactive oxygen species, the release of cytochrome C, and the activation of caspase-3.

Korean journal of urology

Lee JW, Hong HM, Kwon DD, Pae HO, Jeong HJ.
PMID: 21221209
Korean J Urol. 2010 Dec;51(12):870-8. doi: 10.4111/kju.2010.51.12.870. Epub 2010 Dec 21.

PURPOSE: Curcumin (Cur) has been reported to induce apoptosis in human renal carcinoma Caki cells. Dimethoxycurcumin (DMC), one of several synthetic Cur analogues, has been reported to have increased metabolic stability over Cur. We determined whether DMC, like Cur,...

Reduction in Surface Contamination With Cyclophosphamide in 30 US Hospital Pharmacies Following Implementation of a Closed-System Drug Transfer Device.

Hospital pharmacy

Sessink PJ, Trahan J, Coyne JW.
PMID: 24421463
Hosp Pharm. 2013 Mar;48(3):204-12. doi: 10.1310/hpj4803-204.

PURPOSE: In a follow-up to a previous study, surface contamination with the antineoplastic drug cyclophosphamide was compared in 30 US hospital pharmacies from 2004 to 2010 following preparation with standard drug preparation techniques or the PhaSeal closed system drug...

Effect of O.

Molecular and clinical oncology

Kurimoto T, Kondo A, Ogino I, Fujimura J, Arakawa A, Arai H, Shimizu T.
PMID: 29285383
Mol Clin Oncol. 2017 Dec;7(6):1107-1111. doi: 10.3892/mco.2017.1431. Epub 2017 Sep 29.

Medulloblastoma is a highly malignant brain tumor that predominately affects children and requires multimodal treatment, including chemotherapy with alkylating agents. O

Recent Advances in the Neoadjuvant Treatment of Breast Cancer.

Journal of breast cancer

Rubovszky G, Horváth Z.
PMID: 28690648
J Breast Cancer. 2017 Jun;20(2):119-131. doi: 10.4048/jbc.2017.20.2.119. Epub 2017 Jun 26.

In the last few decades, neoadjuvant therapy for breast cancer has gained considerable therapeutic importance. Despite extensive clinical investigations, it has not yet been clarified whether neoadjuvant therapy would result in improved survival in comparison with the standard adjuvant...

Potential of four marine-derived fungi extracts as anti-proliferative and cell death-inducing agents in seven human cancer cell lines.

Asian Pacific journal of tropical medicine

Ramos AA, Prata-Sena M, Castro-Carvalho B, Dethoup T, Buttachon S, Kijjoa A, Rocha E.
PMID: 26522294
Asian Pac J Trop Med. 2015 Oct;8(10):798-806. doi: 10.1016/j.apjtm.2015.09.005. Epub 2015 Sep 25.

OBJECTIVE: To evaluate the in vitro anticancer activity of crude ethyl acetate extracts of the culture of four marine-derived fungi Aspergillus similanensis KUFA 0013 (E1), Neosartorya paulistensis KUFC 7897 (E2), Neosartorya siamensis KUFA 0017 (E4) and Talaromyces trachyspermus KUFC...

Evaluation of Oral Mucositis Occurrence in Oncologic Patients under Antineoplastic Therapy Submitted to the Low-Level Laser Coadjuvant Therapy.

Journal of clinical medicine

Leite Cavalcanti A, José de Macêdo D, Suely Barros Dantas F, Dos Santos Menezes K, Filipe Bezerra Silva D, Alves de Melo Junior W, Fabia Cabral Cavalcanti A.
PMID: 29695071
J Clin Med. 2018 Apr 24;7(5). doi: 10.3390/jcm7050090.

Low-level laser therapy has been widely used in treating many conditions, including oral mucositis. The purpose of this study was to evaluate the occurrence of oral mucositis in patients undergoing antineoplastic therapy submitted to preventive and therapeutic treatment with...

Cutaneous toxicities from targeted therapies used in oncology: Literature review of clinical presentation and management.

International journal of women's dermatology

Huynh Dagher S, Blom A, Chabanol H, Funck-Brentano E.
PMID: 35024416
Int J Womens Dermatol. 2021 Sep 28;7(5):615-624. doi: 10.1016/j.ijwd.2021.09.009. eCollection 2021 Dec.

With the development of molecular targeted therapies, a wide array of dermatologic toxicities is appearing. Their prevention, recognition, and management by dermatologists is critical to ensure antineoplastic treatment continuation. The objective of this study was to provide a literature...

Development of a prediction models for chemotherapy-induced adverse drug reactions: A retrospective observational study using electronic health records.

European journal of oncology nursing : the official journal of European Oncology Nursing Society

On J, Park HA, Yoo S.
PMID: 34861529
Eur J Oncol Nurs. 2021 Nov 20;56:102066. doi: 10.1016/j.ejon.2021.102066. Epub 2021 Nov 20.

PURPOSE: Chemotherapy-induced adverse drug reactions (ADRs) are common and diverse, and not only affect changes or interruptions to treatment schedules, but also negatively affect the patient's quality of life. This study aimed to predict eight chemotherapy-induced ADRs based on...

Showing 1 to 12 of 435 entries