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Showing 1 to 6 of 6 entries
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Establishment of an In Vitro Model of Persistent Chicken Anemia Virus Infection.

Pathogens (Basel, Switzerland)

Van Dong H, Tran GTH, Trinh DQ, Takeda Y, Ogawa H, Imai K.
PMID: 33076262
Pathogens. 2020 Oct 15;9(10). doi: 10.3390/pathogens9100842.

Persistent infection of chicken anemia virus (CAV) in chickens has been suspected to result in immunosuppression and exogenous virus contamination within vaccine production. However, no direct evidence for persistent CAV infection has thus far been obtained. In this study,...

Detection of impaired IgG antibody formation facilitates the decision on early immunoglobulin replacement in hypogammaglobulinemic patients.

Frontiers in immunology

Wolf HM, Thon V, Litzman J, Eibl MM.
PMID: 25699049
Front Immunol. 2015 Feb 02;6:32. doi: 10.3389/fimmu.2015.00032. eCollection 2015.

Hypogammaglobulinemia (serum IgG lower than 2 SD below the age-matched mean) and clinical symptoms such as increased susceptibility to infection, autoimmune manifestations, granulomatous disease, and unexplained polyclonal lymphoproliferation are considered to be diagnostic hallmarks in patients with common variable...

Identification and validation of viral antigens sharing sequence and structural homology with tumor-associated antigens (TAAs).

Journal for immunotherapy of cancer

Ragone C, Manolio C, Cavalluzzo B, Mauriello A, Tornesello ML, Buonaguro FM, Castiglione F, Vitagliano L, Iaccarino E, Ruvo M, Tagliamonte M, Buonaguro L.
PMID: 34049932
J Immunother Cancer. 2021 May;9(5). doi: 10.1136/jitc-2021-002694.

BACKGROUND: The host's immune system develops in equilibrium with both cellular self-antigens and non-self-antigens derived from microorganisms which enter the body during lifetime. In addition, during the years, a tumor may arise presenting to the immune system an additional...

Monoclonal antibody technology: applications in veterinary science.

Biotechnology advances

Mackie DP.
PMID: 14545927
Biotechnol Adv. 1994;12(4):703-10. doi: 10.1016/0734-9750(94)90012-4.

Monoclonal antibodies have revolutionised the study of animals and their diseases. The author looks at the detection of antigen in samples using a range of techniques from indirect fluorescence, through in-situ hybridization to enzyme linked immunosorbent assays. Examples are...

Complete Genome Sequence of Murine Pneumotropic Virus (Polyomaviridae) Clone pKV(37-1).

Genome announcements

Libbey JE, Fujinami RS.
PMID: 27198030
Genome Announc. 2016 May 19;4(3). doi: 10.1128/genomeA.00404-16.

The murine pneumotropic virus genome encoded by the pKV(37-1) clone was sequenced to completion. The regulatory region harbored a mutation not previously reported. The protein coding regions (large and small T antigens, viral proteins 1 to 3) showed multiple...

EpitopeVec: Linear Epitope Prediction Using Deep Protein Sequence Embeddings.

Bioinformatics (Oxford, England)

Bahai A, Asgari E, Mofrad MRK, Kloetgen A, McHardy AC.
PMID: 34180989
Bioinformatics. 2021 Jun 28; doi: 10.1093/bioinformatics/btab467. Epub 2021 Jun 28.

MOTIVATION: B-cell epitopes (BCEs) play a pivotal role in the development of peptide vaccines, immuno-diagnostic reagents, and antibody production, and thus in infectious disease prevention and diagnostics in general. Experimental methods used to determine BCEs are costly and time-consuming....

Showing 1 to 6 of 6 entries