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NTP Toxicology and Carcinogenesis Studies of Primidone (CAS No. 125-33-7) in F344/N Rats and B6C3F1 Mice (Feed Studies).

National Toxicology Program technical report series

[No authors listed]
PMID: 12571687
Natl Toxicol Program Tech Rep Ser. 2000 Sep;476:1-290.

Primidone is used alone or with other anticonvulsants in the control of grand mal, psychomotor, and focal epileptic seizures. It may control grand mal seizures refractory to other anticonvulsant therapy. Primidone was nominated by the National Cancer Institute for...

Toxicology and Carcinogenesis Studies of 5,5-Diphenylhydantoin (CAS No. 57-41-0) (Phenytoin) in F344/N Rats and B6C3F1 Mice (Feed Studies).

National Toxicology Program technical report series

[No authors listed]
PMID: 12621514
Natl Toxicol Program Tech Rep Ser. 1993 Nov;404:1-303.

5,5-Diphenylhydantoin and its sodium salt are primarily used in the treatment of grand mal and psychomotor seizures, often in combination with other anticonvulsants, including phenobarbital. 5,5-Diphenylhydantoin is a suspected human carcinogen and was one of three compounds selected by...

[Antipsychotics in bipolar disorders].


Vacheron-Trystram MN, Braitman A, Cheref S, Auffray L.
PMID: 15627046
Encephale. 2004 Sep-Oct;30(5):417-24. doi: 10.1016/s0013-7006(04)95456-5.

This article is a review of the various treatments that are currently available, in particular in France, for the treatment of bipolar disorders. This article specifically addresses the use of novel antipsychotic agents as alternative therapy to a lithium...

Smallpox vaccination and adverse reactions. Guidance for clinicians.

MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports

Cono J, Casey CG, Bell DM.
PMID: 12617510
MMWR Recomm Rep. 2003 Feb 21;52:1-28.

The guidance in this report is for evaluation and treatment of patients with complications from smallpox vaccination in the preoutbreak setting. Information is also included related to reporting adverse events and seeking specialized consultation and therapies for these events....

Interventions for chronic pruritus of unknown origin.

The Cochrane database of systematic reviews

Andrade A, Kuah CY, Martin-Lopez JE, Chua S, Shpadaruk V, Sanclemente G, Franco JV.
PMID: 31981369
Cochrane Database Syst Rev. 2020 Jan 25;1:CD013128. doi: 10.1002/14651858.CD013128.pub2.

BACKGROUND: Pruritus is a sensation that leads to the desire to scratch; its origin is unknown in 8% to 15% of affected patients. The prevalence of chronic pruritus of unknown origin (CPUO) in individuals with generalised pruritus ranges from...

Impact of protease inhibitor substitution with efavirenz in HIV-infected children: results of the First Pediatric Switch Study.


McComsey G, Bhumbra N, Ma JF, Rathore M, Alvarez A.
PMID: 12612284
Pediatrics. 2003 Mar;111(3):e275-81. doi: 10.1542/peds.111.3.e275.

OBJECTIVE: Simplification of antiretroviral regimen in human immunodeficiency virus (HIV)-infected children has not yet been investigated. In general, children have a more difficult time maintaining viral suppression because of many factors, including frequent nonadherence and less availability of antiretrovirals...

High-dose vitamin D versus placebo to prevent complications in COVID-19 patients: A structured summary of a study protocol for a randomised controlled trial (CARED-TRIAL).


Mariani J, Tajer C, Antonietti L, Inserra F, Ferder L, Manucha W.
PMID: 33522946
Trials. 2021 Feb 01;22(1):111. doi: 10.1186/s13063-021-05073-3.

OBJECTIVES: To evaluate whether a single high dose of oral cholecalciferol improves the respiratory outcomes as compared with placebo among adults COVID-19 patients at moderate risk of clinical complications.TRIAL DESIGN: The CARED trial is an investigator-initiated, multicentre, randomized, parallel,...

Lithium or an atypical antipsychotic drug in the management of treatment-resistant depression: a systematic review and economic evaluation.

Health technology assessment (Winchester, England)

Edwards SJ, Hamilton V, Nherera L, Trevor N.
PMID: 24284258
Health Technol Assess. 2013 Nov;17(54):1-190. doi: 10.3310/hta17540.

BACKGROUND: Patients with treatment-resistant depression (TRD) are those with major depressive disorder that has not responded adequately to treatment. The causes of depression are not fully understood, although there is evidence to suggest that depression is a complex interaction...

Sleep in children with neoplasms of the central nervous system: case review of 14 children.


Rosen GM, Bendel AE, Neglia JP, Moertel CL, Mahowald M.
PMID: 12837905
Pediatrics. 2003 Jul;112(1):e46-54. doi: 10.1542/peds.112.1.e46.

OBJECTIVE: Sleep is a complex neurologic process that is generated by and primarily benefits the brain. Sleep can be disrupted by a wide range of brain injuries, many of which may occur in children with neoplasms of the central...

Neuromodulators for pain management in rheumatoid arthritis.

The Cochrane database of systematic reviews

Richards BL, Whittle SL, Buchbinder R.
PMID: 22258992
Cochrane Database Syst Rev. 2012 Jan 18;1:CD008921. doi: 10.1002/14651858.CD008921.pub2.

BACKGROUND: Pain management is a high priority for patients with rheumatoid arthritis (RA). Despite deficiencies in research data, neuromodulators have gained widespread clinical acceptance as adjuvants in the management of patients with chronic musculoskeletal pain.OBJECTIVES: The aim of this...

Antidepressants for agitation and psychosis in dementia.

The Cochrane database of systematic reviews

Seitz DP, Adunuri N, Gill SS, Gruneir A, Herrmann N, Rochon P.
PMID: 21328305
Cochrane Database Syst Rev. 2011 Feb 16;(2):CD008191. doi: 10.1002/14651858.CD008191.pub2.

BACKGROUND: Agitation and psychosis are common among older adults with dementia and are challenging to manage. At the present time, little is known about the efficacy and safety of antidepressant medications when used to treat these symptoms.OBJECTIVES: To assess...

Rowell's Syndrome Triggered by Omeprazole.

Acta dermatovenerologica Croatica : ADC

Pozharashka J, Dourmishev L, Balabanova M, Vassileva S, Miteva L.
PMID: 31351509
Acta Dermatovenerol Croat. 2019 Jun;27(2):124-126.

Dear Editor, Rowell's syndrome is a rare disease, characterized by the appearance of erythema multiforme (EM)-like lesions in patients with lupus erythematosus. It was initially reported by Rowell (1) in 1963 and its existence as a separate clinical entity...

Showing 1 to 12 of 56561 entries