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Showing 1 to 12 of 21 entries
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Standardized two-step testing of antibody activity in COVID-19 convalescent plasma.

iScience

Gilchuk P, Thomsen I, Yoder S, Brady E, Chappell JD, Stevens LJ, Denison MR, Sutton RE, Chen RE, VanBlargan LA, Suryadevara N, Zost SJ, Schmitz J, Pulley JM, Diamond MS, Rhoads JP, Bernard GR, Self WH, Rice TW, Wheeler AP, Crowe JE, Carnahan RH.
PMID: 34901783
iScience. 2021 Dec 08;103602. doi: 10.1016/j.isci.2021.103602. Epub 2021 Dec 08.

The COVID-19 pandemic revealed an urgent need for rapid profiling of neutralizing antibody responses and development of antibody therapeutics. The current Food and Drug Administration-approved serological tests do not measure antibody-mediated viral neutralization, and there is a need for...

Unexpectedly High Prevalence of Hepatitis C Virus Infection, Southern Laos.

Emerging infectious diseases

Black AP, Khounvisith V, Xaydalasouk K, Sayasinh K, Sausy A, Muller CP, Hübschen JM.
PMID: 34932463
Emerg Infect Dis. 2022 Jan;28(1):256-259. doi: 10.3201/eid2801.211307.

During 2017-2019, a total of 88/753 (11.7%) of patients 5-90 years of age in hospitals in Saravan Province, Laos, were seropositive for hepatitis C virus antibodies. Viral RNA was found in 44 samples. Sequencing showed high diversity within genotype...

Resolution of viral load in mild COVID-19 patients is associated with both innate and adaptive immune responses.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology

Anantharaj A, Gujjar S, Verma N, Khan NA, Shaman H, Sharanabasava P, Das A, Pandey R, Pandey AK, Medigeshi GR.
PMID: 34971849
J Clin Virol. 2021 Dec 21;146:105060. doi: 10.1016/j.jcv.2021.105060. Epub 2021 Dec 21.

Over 90% of the COVID-19 patients manifest mild/moderate symptoms or are asymptomatic. Although comorbidities and dysregulation of immune response have been implicated in severe COVID-19, the host factors that associate with asymptomatic or mild infections have not been characterized....

Fast SARS-CoV-2 Variant Detection Using Snapback Primer High-Resolution Melting.

Diagnostics (Basel, Switzerland)

Lownik JC, Farrar JS, Way GW, McKay A, Roychoudhury P, Greninger AL, Martin RK.
PMID: 34679489
Diagnostics (Basel). 2021 Sep 28;11(10). doi: 10.3390/diagnostics11101788.

SARS-CoV-2, the virus responsible for COVID-19, emerged in late 2019 and has since spread throughout the world, infecting over 200 million people. The fast spread of SARS-CoV-2 showcased the need for rapid and sensitive testing methodologies to help track...

Resolution of viral load in mild COVID-19 patients is associated with both innate and adaptive immune responses.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology

Anantharaj A, Gujjar S, Verma N, Khan NA, Shaman H, Sharanabasava P, Das A, Pandey R, Pandey AK, Medigeshi GR.
PMID: 34971849
J Clin Virol. 2021 Dec 21;146:105060. doi: 10.1016/j.jcv.2021.105060. Epub 2021 Dec 21.

Over 90% of the COVID-19 patients manifest mild/moderate symptoms or are asymptomatic. Although comorbidities and dysregulation of immune response have been implicated in severe COVID-19, the host factors that associate with asymptomatic or mild infections have not been characterized....

Donor-Specific Antibodies Against Donor Human Leukocyte Antigen are Associated with Graft Inflammation but Not with Fibrosis Long-Term After Liver Transplantation: An Analysis of Protocol Biopsies.

Journal of inflammation research

Gül-Klein S, Hegermann H, Röhle R, Schmelzle M, Tacke F, Schöning W, Öllinger R, Dziodzio T, Maier P, Plewe JM, Horst D, Sauer IM, Pratschke J, Lachmann N, Eurich D.
PMID: 34188517
J Inflamm Res. 2021 Jun 23;14:2697-2712. doi: 10.2147/JIR.S307778. eCollection 2021.

BACKGROUND: Donor-specific antibodies (DSA) against donor human leukocyte antigen after liver transplantation, which are associated with histological changes, have been widely studied with respect to their sustained impact on transplant function. However, their long-term impact after liver transplantation remains...

Unexpectedly High Prevalence of Hepatitis C Virus Infection, Southern Laos.

Emerging infectious diseases

Black AP, Khounvisith V, Xaydalasouk K, Sayasinh K, Sausy A, Muller CP, Hübschen JM.
PMID: 34932463
Emerg Infect Dis. 2022 Jan;28(1):256-259. doi: 10.3201/eid2801.211307.

During 2017-2019, a total of 88/753 (11.7%) of patients 5-90 years of age in hospitals in Saravan Province, Laos, were seropositive for hepatitis C virus antibodies. Viral RNA was found in 44 samples. Sequencing showed high diversity within genotype...

Seroprevalence, Genotyping, and Monitoring of Hepatitis C Viral Loads in Patients on Antivirals in Burkina Faso.

Intervirology

Yelemkoure ET, Yonli AT, Sombie HK, Tao I, Zouré AA, Ouattara AK, Sorgho AP, Zongo AW, Zeba MTA, Kiendrebeogo IT, Bado P, Kabré MK, Zohoncon TM, Djigma FW, Obiri-Yeboah D, Simpore J.
PMID: 34583364
Intervirology. 2021 Sep 28; doi: 10.1159/000519848. Epub 2021 Sep 28.

INTRODUCTION: Hepatitis C virus (HCV) infection remains a major public health problem worldwide. In Burkina Faso, nearly 720,000 people are living with HCV, and each year about 900 people die from complications of cirrhosis or hepatocellular carcinoma. This study...

Resolution of viral load in mild COVID-19 patients is associated with both innate and adaptive immune responses.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology

Anantharaj A, Gujjar S, Verma N, Khan NA, Shaman H, Sharanabasava P, Das A, Pandey R, Pandey AK, Medigeshi GR.
PMID: 34971849
J Clin Virol. 2022 Jan;146:105060. doi: 10.1016/j.jcv.2021.105060. Epub 2021 Dec 21.

Over 90% of the COVID-19 patients manifest mild/moderate symptoms or are asymptomatic. Although comorbidities and dysregulation of immune response have been implicated in severe COVID-19, the host factors that associate with asymptomatic or mild infections have not been characterized....

Clinical Trials of Oncolytic Viruses in Breast Cancer.

Frontiers in oncology

Carter ME, Koch A, Lauer UM, Hartkopf AD.
PMID: 35004328
Front Oncol. 2021 Dec 23;11:803050. doi: 10.3389/fonc.2021.803050. eCollection 2021.

Breast cancer is the second most common kind of cancer worldwide and oncolytic viruses may offer a new treatment approach. There are three different types of oncolytic viruses used in clinical trials; (i) oncolytic viruses with natural anti-neoplastic properties;...

Interferon-alpha therapy in Sicilian and Sardinian polytransfused thalassaemic patients with chronic hepatitis C.

BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy

Pizzarelli G, Di Gregorio F, Romeo MA, Carboni F, Gallisai D, Solinas A, Malaguarnera M, Musumeci S.
PMID: 18031162
BioDrugs. 1999 Jul;12(1):55-63. doi: 10.2165/00063030-199912010-00006.

OBJECTIVE: Our study was designed to evaluate the effects of 2 dosage schedules of recombinant interferon (IFN)-alpha (IFNalpha-2a and IFNalpha-2b) in reducing serum ALT and eradicating serum hepatitis C virus (HCV) RNA in beta-thalassaemic patients with chronic hepatitis C.DESIGN:...

Molecular epidemiology of hepatitis C virus and its relation with persistence or clearance of infection in Hamadan, West-Iran.

Iranian journal of microbiology

Solgi G, Sabouri Ghannad M, Khalilian A, Majlesi A, Hajiloo M.
PMID: 26622972
Iran J Microbiol. 2015 Apr;7(2):109-17.

BACKGROUND AND OBJECTIVES: Hepatitis C Virus genotyping appears to be vital for predicting the response to antiviral therapy. The present study aimed to analyze the HCV genotypes in relation to persistence or clearance of the virus in residents of...

Showing 1 to 12 of 21 entries