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Novel Treatment of Radicular Pain With a Multi-Mechanistic Combination Topical Agent: A Case Series and Literature Review.

Anesthesiology and pain medicine

Safaeian P, Mattie R, Hahn M, Plastaras CT, McCormick ZL.
PMID: 27252902
Anesth Pain Med. 2016 Mar 01;6(2):e33322. doi: 10.5812/aapm.33322. eCollection 2016 Apr.

INTRODUCTION: Pharmacologic treatment of radicular pain with oral medications is limited by adverse effects and concern for dependence. While topical formulations have been explored in pain research, there is no published literature evaluating the efficacy in radicular pain. We...

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Safaeian P, Mattie R, Hahn M, et al. Novel Treatment of Radicular Pain With a Multi-Mechanistic Combination Topical Agent: A Case Series and Literature Review. Anesth Pain Med. 2016;6(2):e33322doi: 10.5812/aapm.33322.
Safaeian, P., Mattie, R., Hahn, M., Plastaras, C. T., & McCormick, Z. L. (2016). Novel Treatment of Radicular Pain With a Multi-Mechanistic Combination Topical Agent: A Case Series and Literature Review. Anesthesiology and pain medicine, 6(2), e33322. https://doi.org/10.5812/aapm.33322
Safaeian, Pegah, et al. "Novel Treatment of Radicular Pain With a Multi-Mechanistic Combination Topical Agent: A Case Series and Literature Review." Anesthesiology and pain medicine vol. 6,2 (2016): e33322. doi: https://doi.org/10.5812/aapm.33322
Safaeian P, Mattie R, Hahn M, Plastaras CT, McCormick ZL. Novel Treatment of Radicular Pain With a Multi-Mechanistic Combination Topical Agent: A Case Series and Literature Review. Anesth Pain Med. 2016 Mar 01;6(2):e33322. doi: 10.5812/aapm.33322. eCollection 2016 Apr. PMID: 27252902; PMCID: PMC4886452.
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Comparison of hemodynamic response to adrenaline infiltration in children undergoing cleft palate repair during general anesthesia with sevoflurane and isoflurane.

Journal of anaesthesiology, clinical pharmacology

Gunnam PR, Durga P, Gurajala I, Kaluvala PR, Veerabathula P, Ramachandran G.
PMID: 27006534
J Anaesthesiol Clin Pharmacol. 2016 Jan-Mar;32(1):12-7. doi: 10.4103/0970-9185.175650.

BACKGROUND AND AIMS: Systemic absorption of adrenaline often used for infiltration during cleft palate surgery leads to adverse hemodynamic responses. These hemodynamic responses may be attenuated by the volatile anesthetics. This study aims to compare the hemodynamic responses to...

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Gunnam PR, Durga P, Gurajala I, et al. Comparison of hemodynamic response to adrenaline infiltration in children undergoing cleft palate repair during general anesthesia with sevoflurane and isoflurane. J Anaesthesiol Clin Pharmacol. 2016;32(1):12-7doi: 10.4103/0970-9185.175650.
Gunnam, P. R., Durga, P., Gurajala, I., Kaluvala, P. R., Veerabathula, P., & Ramachandran, G. (2016). Comparison of hemodynamic response to adrenaline infiltration in children undergoing cleft palate repair during general anesthesia with sevoflurane and isoflurane. Journal of anaesthesiology, clinical pharmacology, 32(1), 12-7. https://doi.org/10.4103/0970-9185.175650
Gunnam, Poojita Reddy, et al. "Comparison of hemodynamic response to adrenaline infiltration in children undergoing cleft palate repair during general anesthesia with sevoflurane and isoflurane." Journal of anaesthesiology, clinical pharmacology vol. 32,1 (2016): 12-7. doi: https://doi.org/10.4103/0970-9185.175650
Gunnam PR, Durga P, Gurajala I, Kaluvala PR, Veerabathula P, Ramachandran G. Comparison of hemodynamic response to adrenaline infiltration in children undergoing cleft palate repair during general anesthesia with sevoflurane and isoflurane. J Anaesthesiol Clin Pharmacol. 2016 Jan-Mar;32(1):12-7. doi: 10.4103/0970-9185.175650. PMID: 27006534; PMCID: PMC4784195.
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Effects of Anesthetic Management on Early Postoperative Recovery, Hemodynamics and Pain After Supratentorial Craniotomy.

Journal of clinical medicine research

Ayrian E, Kaye AD, Varner CL, Guerra C, Vadivelu N, Urman RD, Zelman V, Lumb PD, Rosa G, Bilotta F.
PMID: 26345202
J Clin Med Res. 2015 Oct;7(10):731-41. doi: 10.14740/jocmr2256w. Epub 2015 Aug 23.

Various clinical trials have assessed how intraoperative anesthetics can affect early recovery, hemodynamics and nociception after supratentorial craniotomy. Whether or not the difference in recovery pattern differs in a meaningful way with anesthetic choice is controversial. This review examines...

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Ayrian E, Kaye AD, Varner CL, et al. Effects of Anesthetic Management on Early Postoperative Recovery, Hemodynamics and Pain After Supratentorial Craniotomy. J Clin Med Res. 2015;7(10):731-41doi: 10.14740/jocmr2256w.
Ayrian, E., Kaye, A. D., Varner, C. L., Guerra, C., Vadivelu, N., Urman, R. D., Zelman, V., Lumb, P. D., Rosa, G., & Bilotta, F. (2015). Effects of Anesthetic Management on Early Postoperative Recovery, Hemodynamics and Pain After Supratentorial Craniotomy. Journal of clinical medicine research, 7(10), 731-41. https://doi.org/10.14740/jocmr2256w
Ayrian, Eugenia, et al. "Effects of Anesthetic Management on Early Postoperative Recovery, Hemodynamics and Pain After Supratentorial Craniotomy." Journal of clinical medicine research vol. 7,10 (2015): 731-41. doi: https://doi.org/10.14740/jocmr2256w
Ayrian E, Kaye AD, Varner CL, Guerra C, Vadivelu N, Urman RD, Zelman V, Lumb PD, Rosa G, Bilotta F. Effects of Anesthetic Management on Early Postoperative Recovery, Hemodynamics and Pain After Supratentorial Craniotomy. J Clin Med Res. 2015 Oct;7(10):731-41. doi: 10.14740/jocmr2256w. Epub 2015 Aug 23. PMID: 26345202; PMCID: PMC4554211.
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[Cytotoxic effects of local anesthesia through lidocaine/ropivacaine on human melanoma cell lines].

Revista brasileira de anestesiologia

Kang DK, Zhao LY, Wang HL.
PMID: 27639508
Rev Bras Anestesiol. 2016 Nov - Dec;66(6):594-602. doi: 10.1016/j.bjan.2016.08.002. Epub 2016 Sep 14.

BACKGROUND: Local anesthetics (LAs) are generally considered as safe, but cytotoxicity has been reported for several local anesthetics used in humans, which is not well investigated. In the present study, the cytotoxicity of lidocaine, ropivacaine and the combination of...

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Kang DK, Zhao LY, Wang HL. Efeitos citotóxicos de anestesia local com lidocaína/ropivacaína em linhagens celulares de melanoma humano. [Cytotoxic effects of local anesthesia through lidocaine/ropivacaine on human melanoma cell lines]. Rev Bras Anestesiol. 2016;66(6):594-602doi: 10.1016/j.bjan.2016.08.002.
Kang, D. K., Zhao, L. Y., & Wang, H. L. (2016). Efeitos citotóxicos de anestesia local com lidocaína/ropivacaína em linhagens celulares de melanoma humano. [Cytotoxic effects of local anesthesia through lidocaine/ropivacaine on human melanoma cell lines]. Revista brasileira de anestesiologia, 66(6), 594-602. https://doi.org/10.1016/j.bjan.2016.08.002
Kang, Ding-Kun, et al. "Efeitos citotóxicos de anestesia local com lidocaína/ropivacaína em linhagens celulares de melanoma humano." [Cytotoxic effects of local anesthesia through lidocaine/ropivacaine on human melanoma cell lines]. Revista brasileira de anestesiologia vol. 66,6 (2016): 594-602. doi: https://doi.org/10.1016/j.bjan.2016.08.002
Kang DK, Zhao LY, Wang HL. Efeitos citotóxicos de anestesia local com lidocaína/ropivacaína em linhagens celulares de melanoma humano. [Cytotoxic effects of local anesthesia through lidocaine/ropivacaine on human melanoma cell lines]. Rev Bras Anestesiol. 2016 Nov - Dec;66(6):594-602. doi: 10.1016/j.bjan.2016.08.002. Epub 2016 Sep 14. Portuguese. PMID: 27639508.
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Solubility of volatile anesthetics in plasma substitutes, albumin, intravenous fat emulsions, perfluorochemical emulsion, and aqueous solutions.

Journal of anesthesia

Shim JC, Kaminoh Y, Tashiro C, Miyamoto Y, Yoo HK.
PMID: 28921091
J Anesth. 1996 Dec;10(4):276-281. doi: 10.1007/BF02483395.

Using the gas chromatographic headspace sampling technique, we determined the solubility of volatile anesthetics (halothane, enflurane, isoflurane, and sevoflurane) in plasma substitutes, albumin solution, intravenous fat emulsions, perfluorochemical FC-43 emulsion, and aqueous solutions at 37°C. The order of magnitude...

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Shim JC, Kaminoh Y, Tashiro C, et al. Solubility of volatile anesthetics in plasma substitutes, albumin, intravenous fat emulsions, perfluorochemical emulsion, and aqueous solutions. J Anesth. 1996;10(4):276-281doi: 10.1007/BF02483395.
Shim, J. C., Kaminoh, Y., Tashiro, C., Miyamoto, Y., & Yoo, H. K. (1996). Solubility of volatile anesthetics in plasma substitutes, albumin, intravenous fat emulsions, perfluorochemical emulsion, and aqueous solutions. Journal of anesthesia, 10(4), 276-281. https://doi.org/10.1007/BF02483395
Shim, Jaes Chol, et al. "Solubility of volatile anesthetics in plasma substitutes, albumin, intravenous fat emulsions, perfluorochemical emulsion, and aqueous solutions." Journal of anesthesia vol. 10,4 (1996): 276-281. doi: https://doi.org/10.1007/BF02483395
Shim JC, Kaminoh Y, Tashiro C, Miyamoto Y, Yoo HK. Solubility of volatile anesthetics in plasma substitutes, albumin, intravenous fat emulsions, perfluorochemical emulsion, and aqueous solutions. J Anesth. 1996 Dec;10(4):276-281. doi: 10.1007/BF02483395. PMID: 28921091.
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Effects and interaction of nicardipine and volatile anesthetics in the rat heart-lung preparation.

Journal of anesthesia

Kashimoto S, Nakamura T, Kume M, Nonaka A, Kumazawa T.
PMID: 28921205
J Anesth. 1994 Mar;8(1):78-83. doi: 10.1007/BF02482760.

The effects of the calcium channel blocker nicardipine (N) and the volatile anesthetics halothane (H), enflurane (E), isoflurane (I), and sevoflurane (S) on myocardial metabolism after postischemic reperfusion were assessed in the isolated rat heart-lung preparation. Wistar-ST rats were...

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Kashimoto S, Nakamura T, Kume M, et al. Effects and interaction of nicardipine and volatile anesthetics in the rat heart-lung preparation. J Anesth. 1994;8(1):78-83doi: 10.1007/BF02482760.
Kashimoto, S., Nakamura, T., Kume, M., Nonaka, A., & Kumazawa, T. (1994). Effects and interaction of nicardipine and volatile anesthetics in the rat heart-lung preparation. Journal of anesthesia, 8(1), 78-83. https://doi.org/10.1007/BF02482760
Kashimoto, Satoshi, et al. "Effects and interaction of nicardipine and volatile anesthetics in the rat heart-lung preparation." Journal of anesthesia vol. 8,1 (1994): 78-83. doi: https://doi.org/10.1007/BF02482760
Kashimoto S, Nakamura T, Kume M, Nonaka A, Kumazawa T. Effects and interaction of nicardipine and volatile anesthetics in the rat heart-lung preparation. J Anesth. 1994 Mar;8(1):78-83. doi: 10.1007/BF02482760. PMID: 28921205.
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In Vitro Toxicity of Local Anesthetics and Corticosteroids on Chondrocyte and Synoviocyte Viability and Metabolism.

Cartilage

Sherman SL, Khazai RS, James CH, Stoker AM, Flood DL, Cook JL.
PMID: 26425261
Cartilage. 2015 Oct;6(4):233-40. doi: 10.1177/1947603515594453.

OBJECTIVE: There is growing concern that intra-articular injection of local anesthetic and/or corticosteroids may cause significant morbidity, including potential toxicity to chondrocytes and synoviocytes, after even a single exposure. We demonstrate that full thickness canine chondral and synovial samples...

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Sherman SL, Khazai RS, James CH, et al. In Vitro Toxicity of Local Anesthetics and Corticosteroids on Chondrocyte and Synoviocyte Viability and Metabolism. Cartilage. 2015;6(4):233-40doi: 10.1177/1947603515594453.
Sherman, S. L., Khazai, R. S., James, C. H., Stoker, A. M., Flood, D. L., & Cook, J. L. (2015). In Vitro Toxicity of Local Anesthetics and Corticosteroids on Chondrocyte and Synoviocyte Viability and Metabolism. Cartilage, 6(4), 233-40. https://doi.org/10.1177/1947603515594453
Sherman, Seth L, et al. "In Vitro Toxicity of Local Anesthetics and Corticosteroids on Chondrocyte and Synoviocyte Viability and Metabolism." Cartilage vol. 6,4 (2015): 233-40. doi: https://doi.org/10.1177/1947603515594453
Sherman SL, Khazai RS, James CH, Stoker AM, Flood DL, Cook JL. In Vitro Toxicity of Local Anesthetics and Corticosteroids on Chondrocyte and Synoviocyte Viability and Metabolism. Cartilage. 2015 Oct;6(4):233-40. doi: 10.1177/1947603515594453. PMID: 26425261; PMCID: PMC4568732.
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Lidocaine versus ropivacaine for postoperative continuous paravertebral nerve blocks in patients undergoing laparoscopic bowel surgery: a randomized, controlled, double-blinded, pilot study.

Local and regional anesthesia

Ghisi D, Fanelli A, Jouguelet-Lacoste J, La Colla L, Auroux AS, Chelly JE.
PMID: 26396544
Local Reg Anesth. 2015 Sep 14;8:71-7. doi: 10.2147/LRA.S84476. eCollection 2015.

BACKGROUND AND OBJECTIVES: Lidocaine could provide many advantages in continuous regional anesthesia techniques, including faster onset, greater titratability, and lower cost than long-acting local anesthetics. This prospective, randomized, double-blinded, pilot study is therefore intended to compare lidocaine to ropivacaine...

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Ghisi D, Fanelli A, Jouguelet-Lacoste J, et al. Lidocaine versus ropivacaine for postoperative continuous paravertebral nerve blocks in patients undergoing laparoscopic bowel surgery: a randomized, controlled, double-blinded, pilot study. Local Reg Anesth. 2015;8:71-7doi: 10.2147/LRA.S84476.
Ghisi, D., Fanelli, A., Jouguelet-Lacoste, J., La Colla, L., Auroux, A. S., & Chelly, J. E. (2015). Lidocaine versus ropivacaine for postoperative continuous paravertebral nerve blocks in patients undergoing laparoscopic bowel surgery: a randomized, controlled, double-blinded, pilot study. Local and regional anesthesia, 871-7. https://doi.org/10.2147/LRA.S84476
Ghisi, Daniela, et al. "Lidocaine versus ropivacaine for postoperative continuous paravertebral nerve blocks in patients undergoing laparoscopic bowel surgery: a randomized, controlled, double-blinded, pilot study." Local and regional anesthesia vol. 8 (2015): 71-7. doi: https://doi.org/10.2147/LRA.S84476
Ghisi D, Fanelli A, Jouguelet-Lacoste J, La Colla L, Auroux AS, Chelly JE. Lidocaine versus ropivacaine for postoperative continuous paravertebral nerve blocks in patients undergoing laparoscopic bowel surgery: a randomized, controlled, double-blinded, pilot study. Local Reg Anesth. 2015 Sep 14;8:71-7. doi: 10.2147/LRA.S84476. eCollection 2015. PMID: 26396544; PMCID: PMC4574900.
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The Analgesic Efficacy of Intrathecal Bupivacaine and Fentanyl with Added Neostigmine or Magnesium Sulphate.

Anesthesiology and pain medicine

Mokaram Dori M, Foruzin F.
PMID: 28975069
Anesth Pain Med. 2016 Sep 18;6(6):e9651. doi: 10.5812/aapm.9651. eCollection 2016 Dec.

BACKGROUND: An appropriate anesthesia duration with minimal side effects and prolonged postoperative analgesia are the ideal characteristics of an intrathecal drug used during spinal anesthesia. Neostigmine and magnesium sulphate have been used as spinal anesthetic additives with narcotics and...

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Mokaram Dori M, Foruzin F. The Analgesic Efficacy of Intrathecal Bupivacaine and Fentanyl with Added Neostigmine or Magnesium Sulphate. Anesth Pain Med. 2016;6(6):e9651doi: 10.5812/aapm.9651.
Mokaram Dori, M., & Foruzin, F. (2016). The Analgesic Efficacy of Intrathecal Bupivacaine and Fentanyl with Added Neostigmine or Magnesium Sulphate. Anesthesiology and pain medicine, 6(6), e9651. https://doi.org/10.5812/aapm.9651
Mokaram Dori, Mehrdad, and Foruzin, Farid. "The Analgesic Efficacy of Intrathecal Bupivacaine and Fentanyl with Added Neostigmine or Magnesium Sulphate." Anesthesiology and pain medicine vol. 6,6 (2016): e9651. doi: https://doi.org/10.5812/aapm.9651
Mokaram Dori M, Foruzin F. The Analgesic Efficacy of Intrathecal Bupivacaine and Fentanyl with Added Neostigmine or Magnesium Sulphate. Anesth Pain Med. 2016 Sep 18;6(6):e9651. doi: 10.5812/aapm.9651. eCollection 2016 Dec. PMID: 28975069; PMCID: PMC5560647.
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Effects of biogenic amines and intravenous anesthetics on the activity of rat locus coeruleus neurons in vitro.

Journal of anesthesia

Ohta Y, Yamamura T, Santos Alojado E, Kemmotsu O.
PMID: 28921147
J Anesth. 1994 Jun;8(2):213-218. doi: 10.1007/BF02514716.

To examine the effects of biogenic amines and clinically relevant concentrations of intravenous anesthetics on neuronal activities, the authors analyzed both spontaneous and evoked activities of neurons in the nucleus locus coeruleus (LC)in vitro using a single unit recording...

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Ohta Y, Yamamura T, Santos Alojado E, et al. Effects of biogenic amines and intravenous anesthetics on the activity of rat locus coeruleus neurons in vitro. J Anesth. 1994;8(2):213-218doi: 10.1007/BF02514716.
Ohta, Y., Yamamura, T., Santos Alojado, E., & Kemmotsu, O. (1994). Effects of biogenic amines and intravenous anesthetics on the activity of rat locus coeruleus neurons in vitro. Journal of anesthesia, 8(2), 213-218. https://doi.org/10.1007/BF02514716
Ohta, Yoshihiro, et al. "Effects of biogenic amines and intravenous anesthetics on the activity of rat locus coeruleus neurons in vitro." Journal of anesthesia vol. 8,2 (1994): 213-218. doi: https://doi.org/10.1007/BF02514716
Ohta Y, Yamamura T, Santos Alojado E, Kemmotsu O. Effects of biogenic amines and intravenous anesthetics on the activity of rat locus coeruleus neurons in vitro. J Anesth. 1994 Jun;8(2):213-218. doi: 10.1007/BF02514716. PMID: 28921147.
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Halothane suppresses the increase in intracellular calcium concentration of isolated rat myocytes during hydrogen peroxide perfusion.

Journal of anesthesia

Nonaka A, Kashimoto S, Iwashita H, Kumazawa T.
PMID: 28921228
J Anesth. 1995 Sep;9(3):260-264. doi: 10.1007/BF02479875.

Ischemia-reperfusion injury is probably caused by the generation of oxygen free radicals. The final common pathway to cell injury may be mediated by intracellular calcium overloading induced by oxygen free radicals. Volatile anesthetics have been shown to improve myocardial...

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Nonaka A, Kashimoto S, Iwashita H, et al. Halothane suppresses the increase in intracellular calcium concentration of isolated rat myocytes during hydrogen peroxide perfusion. J Anesth. 1995;9(3):260-264doi: 10.1007/BF02479875.
Nonaka, A., Kashimoto, S., Iwashita, H., & Kumazawa, T. (1995). Halothane suppresses the increase in intracellular calcium concentration of isolated rat myocytes during hydrogen peroxide perfusion. Journal of anesthesia, 9(3), 260-264. https://doi.org/10.1007/BF02479875
Nonaka, Akihiko, et al. "Halothane suppresses the increase in intracellular calcium concentration of isolated rat myocytes during hydrogen peroxide perfusion." Journal of anesthesia vol. 9,3 (1995): 260-264. doi: https://doi.org/10.1007/BF02479875
Nonaka A, Kashimoto S, Iwashita H, Kumazawa T. Halothane suppresses the increase in intracellular calcium concentration of isolated rat myocytes during hydrogen peroxide perfusion. J Anesth. 1995 Sep;9(3):260-264. doi: 10.1007/BF02479875. PMID: 28921228.
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Efficacy of subpleural continuous infusion of local anesthetics after thoracoscopic pulmonary resection for primary lung cancer compared to intravenous patient-controlled analgesia.

Journal of thoracic disease

Jung J, Park SY, Haam S.
PMID: 27499973
J Thorac Dis. 2016 Jul;8(7):1814-9. doi: 10.21037/jtd.2016.06.16.

BACKGROUND: This study compared the efficacy and side effects of intravenous patient-controlled analgesia (IV-PCA) with those of a subpleural continuous infusion of local anesthetic (ON-Q system) in patients undergoing thoracoscopic pulmonary resection for primary lung cancer.METHODS: We retrospectively reviewed...

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Jung J, Park SY, Haam S. Efficacy of subpleural continuous infusion of local anesthetics after thoracoscopic pulmonary resection for primary lung cancer compared to intravenous patient-controlled analgesia. J Thorac Dis. 2016;8(7):1814-9doi: 10.21037/jtd.2016.06.16.
Jung, J., Park, S. Y., & Haam, S. (2016). Efficacy of subpleural continuous infusion of local anesthetics after thoracoscopic pulmonary resection for primary lung cancer compared to intravenous patient-controlled analgesia. Journal of thoracic disease, 8(7), 1814-9. https://doi.org/10.21037/jtd.2016.06.16
Jung, Joonho, et al. "Efficacy of subpleural continuous infusion of local anesthetics after thoracoscopic pulmonary resection for primary lung cancer compared to intravenous patient-controlled analgesia." Journal of thoracic disease vol. 8,7 (2016): 1814-9. doi: https://doi.org/10.21037/jtd.2016.06.16
Jung J, Park SY, Haam S. Efficacy of subpleural continuous infusion of local anesthetics after thoracoscopic pulmonary resection for primary lung cancer compared to intravenous patient-controlled analgesia. J Thorac Dis. 2016 Jul;8(7):1814-9. doi: 10.21037/jtd.2016.06.16. PMID: 27499973; PMCID: PMC4958826.
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Showing 1 to 12 of 2289 entries