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Showing 1 to 12 of 1653 entries
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Dopamine transporter and vesicular monoamine transporter knockout mice : implications for Parkinson's disease.

Methods in molecular medicine

Miller GW, Wang YM, Gainetdinov RR, Caron MG.
PMID: 21318776
Methods Mol Med. 2001;62:179-90. doi: 10.1385/1-59259-142-6:179.

One of the most valuable methods for understanding the function of a particular protein is the generation of animals that have had the gene encoding for the protein of interest disrupted, commonly known as a "quo;knockout"quo; or null mutant....

Antagonism of Low Dose Amphetamine Disruption of Latent Inhibition in Rats By Haloperidol, and By the 5Ht-3 Antagonist, Ondansetron: Warburton EC, Feldon J*, Weiner I*, Gray JA, Joseph MH MRC Brain, Behaviour and Psychiatry Research Group, Dept of Psychology, Institute of Psychiatry, London, SE5 8AF and *Dept of Psychology, University of Tel Aviv, Israel.

Journal of psychopharmacology (Oxford, England)

[No authors listed]
PMID: 22291268
J Psychopharmacol. 1992 Jan;6(1):110. doi: 10.1177/026988119200600140.

No abstract available.

20-year outcomes in adolescents who self-harm: a population-based cohort study.

The Lancet. Child & adolescent health

Borschmann R, Becker D, Coffey C, Spry E, Moreno-Betancur M, Moran P, Patton GC.
PMID: 30169168
Lancet Child Adolesc Health. 2017 Nov;1(3):195-202. doi: 10.1016/S2352-4642(17)30007-X. Epub 2017 Jul 08.

BACKGROUND: Little is known about the long-term psychosocial outcomes associated with self-harm during adolescence. We aimed to determine whether adolescents who self-harm are at increased risk of adverse psychosocial outcomes in the fourth decade of life, using data from...

Modafinil : A Review of its Pharmacology and Clinical Efficacy in the Management of Narcolepsy.

CNS drugs

McClellan KJ, Spencer CM.
PMID: 27521015
CNS Drugs. 1998 Apr;9(4):311-24. doi: 10.2165/00023210-199809040-00006.

SYNOPSIS: Modafinil promotes wakefulness through an as yet unknown mechanism of action. It significantly increases daytime sleep latency and reduces excessive daytime sleepiness (EDS) compared with placebo in patients with narcolepsy. However, the drug does not suppress cataplexy. Although...

The Disruptive Effect of Low Dose Amphetamine On Latent Inhibition in the Rat, Demonstrated in a Novel Within-Subject Paradigm: Young AMJ, Frangou S, Warburton EC, Joseph MH MRC Brain, Behaviour and Psychiatry Group, Departments of Psychology and Neuroscience, Institute of Psychiatry, London SE5 8AF.

Journal of psychopharmacology (Oxford, England)

[No authors listed]
PMID: 22291274
J Psychopharmacol. 1992 Jan;6(1):113. doi: 10.1177/026988119200600146.

No abstract available.

N-methyl-1-(1,3-benzodioxol-5-yl)-2-butanamine (MBDB): its properties and possible risks.

Addiction biology

Aerts LA, Mallaret M, Rigter H.
PMID: 20575841
Addict Biol. 2000 Jul 01;5(3):269-82. doi: 10.1111/j.1369-1600.2000.tb00191.x.

Abstract MBDB (N -methyl-1-(1,3-benzodioxol-5-yl)-2-aminobutane) is the alpha-ethyl homologue of MDMA (3,4-methylenedioxy-N-methylamphetamine). MBDB is metabolized and excreted similarly to MDMA: presumably, the majority of oral MBDB is excreted in urine unmetabolized.The main metabolic routes in man are thought to be...

Psychostimulant drugs for cocaine dependence.

The Cochrane database of systematic reviews

Castells X, Cunill R, Pérez-Mañá C, Vidal X, Capellà D.
PMID: 27670244
Cochrane Database Syst Rev. 2016 Sep 27;9:CD007380. doi: 10.1002/14651858.CD007380.pub4.

BACKGROUND: Cocaine dependence is a severe disorder for which no medication has been approved. Like opioids for heroin dependence, replacement therapy with psychostimulants could be an effective therapy for treatment.OBJECTIVES: To assess the effects of psychostimulants for cocaine abuse...

Mobile Phone, Computer, and Internet Use Among Older Homeless Adults: Results from the HOPE HOME Cohort Study.

JMIR mHealth and uHealth

Raven MC, Kaplan LM, Rosenberg M, Tieu L, Guzman D, Kushel M.
PMID: 30530464
JMIR Mhealth Uhealth. 2018 Dec 10;6(12):e10049. doi: 10.2196/10049.

BACKGROUND: The median age of single homeless adults is approximately 50 years. Older homeless adults have poor social support and experience a high prevalence of chronic disease, depression, and substance use disorders. Access to mobile phones and the internet...

Substance Abuse and the HIV Situation in Malaysia.

Journal of food and drug analysis

Singh D, Chawarski MC, Schottenfeld R, Vicknasingam B.
PMID: 25278737
J Food Drug Anal. 2013 Dec;21(4):S46-S51. doi: 10.1016/j.jfda.2013.09.033.

Heroin continues to be the main drug used in Malaysia, while amphetamine-type stimulants (ATS) have been recently identified as a growing problem. A cumulative total of 300,241 drug users were detected between 1988 and 2006. It is also estimated...

Correction: Hoops et al., Dopamine Development in the Mouse Orbital Prefrontal Cortex is Protracted and Sensitive to Amphetamine in Adolescence (eNeuro January/February 2018, 5(1) e0372-17.2017 1-9 https://doi.org/10.1523/ENEURO.0372-17.2017.

eNeuro

[No authors listed]
PMID: 29488511
eNeuro. 2018 Feb 26;5(1). doi: 10.1523/ENEURO.0026-18.2018. eCollection 2018.

[This corrects the article DOI: 10.1523/ENEURO.0372-17.2017.][This corrects the article DOI: 10.1523/ENEURO.0372-17.2017.].

Evaluation of Attention-Deficit/Hyperactivity Disorder Medications, Externalizing Symptoms, and Suicidality in Children.

JAMA network open

Shoval G, Visoki E, Moore TM, DiDomenico GE, Argabright ST, Huffnagle NJ, Alexander-Bloch AF, Waller R, Keele L, Benton TD, Gur RE, Barzilay R.
PMID: 34086035
JAMA Netw Open. 2021 Jun 01;4(6):e2111342. doi: 10.1001/jamanetworkopen.2021.11342.

IMPORTANCE: Childhood suicidality (ie, suicidal ideation or attempts) rates are increasing, and attention-deficit/hyperactivity disorder (ADHD) and externalizing symptoms are common risk factors associated with suicidality. More data are needed to describe associations of ADHD pharmacotherapy with childhood suicidality.OBJECTIVE: To...

Othello Syndrome: Delusional Disorder - Jealous Type ≠ Violence.

CNS spectrums

Ahn ES, Hobbs JA.
PMID: 34127129
CNS Spectr. 2021 Apr;26(2):160-161. doi: 10.1017/S1092852920002588.

BACKGROUND: Othello syndrome, also known as morbid jealousy, pathological jealousy, and conjugal paranoia, is a rare delusional disorder related to partner's infidelity. There are no large scale or comprehensive studies on delusional jealousy, and only few case reports and...

Showing 1 to 12 of 1653 entries