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Showing 1 to 12 of 514 entries
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Diagnosis and Treatment of Childhood Migraine.

Current treatment options in neurology

Merison K, Jacobs H.
PMID: 27704257
Curr Treat Options Neurol. 2016 Nov;18(11):48. doi: 10.1007/s11940-016-0431-4.

OPINION STATEMENT: While the diagnosis of migraine in children is generally straightforward, treatment can seem complex with a number of medication choices, many of which are used "off label." Patients with intermittent migraines can often be managed with ibuprofen...

Hydrophilic interaction chromatography: A promising alternative to reversed-phase liquid chromatography systems for the purification of small protonated bases.

Journal of separation science

Gritti F, Guiochon G.
PMID: 25755153
J Sep Sci. 2015 May;38(10):1633-41. doi: 10.1002/jssc.201401351. Epub 2015 Apr 14.

The overloaded band profiles of the protonated species of propranolol and amitriptyline were recorded under acidic conditions on four classes of stationary phases including a conventional silica/organic hybrid material in reversed-phase liquid chromatography mode (BEH-C18), an electrostatic repulsion reversed-phase...

Amitriptyline 2% cream vs. capsaicin 0.75% cream in the treatment of painful diabetic neuropathy (Double blind, randomized clinical trial of efficacy and safety).

Iranian journal of pharmaceutical research : IJPR

Kiani J, Ahmad Nasrollahi S, Esna-Ashari F, Fallah P, Sajedi F.
PMID: 26664395
Iran J Pharm Res. 2015;14(4):1263-8.

Because of less systemic side effects of topical medications in pain relief of the painful form of diabetic peripheral neuropathy, this study aimed to compare the effect of amitriptyline and capsaicin cream in relieving pain in this condition. In...

Two lessons from the empiric management of a combined overdose of liraglutide and amitriptyline.

A & A case reports

Bowler M, Nethercott DR.
PMID: 25611153
A A Case Rep. 2014 Feb 01;2(3):28-30. doi: 10.1097/ACC.0b013e3182a526fa.

We report the case of a 52-year-old man with a combined liraglutide and amitriptyline overdose who presented with a seizure and then pulseless electrical activity cardiac arrest. This is the largest reported overdose of liraglutide (36 mg), a novel...

Potentially inappropriate medication prescribed to elderly outpatients at a general medicine unit.

Einstein (Sao Paulo, Brazil)

Faustino CG, Martins Mde A, Jacob Filho W.
PMID: 26760548
Einstein (Sao Paulo). 2011 Mar;9(1):18-23. doi: 10.1590/S1679-45082011AO1844.

OBJECTIVE: To establish the prevalence of potentially inappropriate medications prescribed for elderly patients, to identify the most commonly involved drugs, and to investigate whether age, sex and number of medications were related with the prescription of these drugs.METHODS: Prescriptions...

Management of Neuropathic Pain Associated with Spinal Cord Injury.

Pain and therapy

Hagen EM, Rekand T.
PMID: 25744501
Pain Ther. 2015 Jun;4(1):51-65. doi: 10.1007/s40122-015-0033-y. Epub 2015 Mar 06.

Spinal cord injury (SCI) is an injury to the spinal cord that leads to varying degrees of motor and/or sensory deficits and paralysis. Chronic pain of both neuropathic and nociceptive type is common and contributes to reduced quality of...

Inappropriate medicine prescribing in older South Africans: A cross-sectional analysis of medicine claims data.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde

Van Heerden JA, Burger JR, Gerber JJ.
PMID: 27725022
S Afr Med J. 2016 Sep 09;106(10):1010-1016. doi: 10.7196/SAMJ.2016.v106i10.10627.

BACKGROUND: Prescribing for older patients is a well-recognised problem, and inappropriate items are prescribed frequently. Several tools and criteria are available to promote rational prescribing in older patients.OBJECTIVE: To determine the prevalence of potentially inappropriate prescriptions (PIPs) in older...

Clinical Pharmacogenetics of Cytochrome P450-Associated Drugs in Children.

Journal of personalized medicine

Aka I, Bernal CJ, Carroll R, Maxwell-Horn A, Oshikoya KA, Van Driest SL.
PMID: 29099060
J Pers Med. 2017 Nov 02;7(4). doi: 10.3390/jpm7040014.

Cytochrome P450 (CYP) enzymes are commonly involved in drug metabolism, and genetic variation in the genes encoding CYPs are associated with variable drug response. While genotype-guided therapy has been clinically implemented in adults, these associations are less well established...

Paroxetine versus amitriptyline in patients with recurrent major depression: A double-blind trial.

International journal of psychiatry in clinical practice

Sacchetti E, Cassano GB, Penati G, Pavan L, Nardini M, Casacchia M, Pancheri P, Muscettola G, Faravelli C, Aguglia E, Nivoli G, Ravizza L, Castrogiovanni P.
PMID: 24931886
Int J Psychiatry Clin Pract. 2002;6(1):23-9. doi: 10.1080/136515002753489380.

INTRODUCTION: Long-term exposure to antidepressants is required to prevent relapses and recurrences in patients with recurrent major depression. Furthermore, a good pharmacological compliance is the key to successful long-term treatment. Since the early phases of a treatment influence long-term...

Effects of repeated dosing with mechanistically distinct antinociceptive ligands in a rat model of neuropathic spinal cord injury pain.

Pharmacology research & perspectives

Hama AT, Pearson JP, Sagen J.
PMID: 25505583
Pharmacol Res Perspect. 2014 Apr;2(2):e00034. doi: 10.1002/prp2.34. Epub 2014 Mar 13.

A lack of efficacy of some analgesic drugs has been previously described in rats with neuropathic spinal cord injury (SCI) pain. It has been suggested that repeated dosing in these animals over time may eventually lead to efficacy. However,...

A new effective on chip electromembrane extraction coupled with high performance liquid chromatography for enhancement of extraction efficiency.

Analytica chimica acta

Abdossalami Asl Y, Yamini Y, Seidi S, Ebrahimpour B.
PMID: 26526909
Anal Chim Acta. 2015 Oct 22;898:42-9. doi: 10.1016/j.aca.2015.09.052. Epub 2015 Oct 09.

In the present research, an effective on chip electromembrane extraction (CEME) coupled with high performance liquid chromatography was presented for analysis of nortriptyline (NOR) and amitriptyline (AMI) as basic model analytes from urine samples. The chip consists of two...

Pharmacological Evaluation of Antidepressant-Like Effect of Genistein and Its Combination with Amitriptyline: An Acute and Chronic Study.

Advances in pharmacological sciences

Gupta G, Jia Jia T, Yee Woon L, Kumar Chellappan D, Candasamy M, Dua K.
PMID: 26681936
Adv Pharmacol Sci. 2015;2015:164943. doi: 10.1155/2015/164943. Epub 2015 Nov 22.

The present study was designed to evaluate the acute and chronic antidepressant effect of genistein in combination with amitriptyline in mice. Animals were divided into six groups (n = 6) for treatment with water, genistein, or amitriptyline, either alone...

Showing 1 to 12 of 514 entries