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Showing 1 to 12 of 2536 entries
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Suppression of aldosterone synthesis and secretion by ca(2+) channel antagonists.

International journal of endocrinology

Ikeda K, Isaka T, Fujioka K, Manome Y, Tojo K.
PMID: 23097668
Int J Endocrinol. 2012;2012:519467. doi: 10.1155/2012/519467. Epub 2012 Oct 11.

Aldosterone, a specific mineralocorticoid receptor (MR) agonist and a key player in the development of hypertension, is synthesized as a final product of renin-angiotensin-aldosterone system. Hypertension can be generally treated by negating the effects of angiotensin II through the...

Unilateral adrenal hyperplasia is a usual cause of primary hyperaldosteronism. Results from a Swedish screening study.

BMC endocrine disorders

Sigurjonsdottir HA, Gronowitz M, Andersson O, Eggertsen R, Herlitz H, Sakinis A, Wangberg B, Johannsson G.
PMID: 22958674
BMC Endocr Disord. 2012 Sep 08;12:17. doi: 10.1186/1472-6823-12-17.

BACKGROUND: The existence of unilateral adrenal hyperplasia (AH) has been considered a rare cause of primary hyperaldosteronism (PA).METHODS: In a prospective study we screened for PA in a non-selected (NSP) and selected hypertensive population (SP), to define the cause...

Sodium handling is associated with liver function impairment and renin-aldosterone axis activity in patients with preascitic cirrhosis without hyponatremia.

Annals of gastroenterology

Tzamouranis D, Alexopoulou A, Dourakis SP, Stergiou GS.
PMID: 24713869
Ann Gastroenterol. 2012;25(3):254-257.

BACKGROUND: In cirrhotic patients awaiting liver transplantation, serum sodium concentration is related to prognosis. However, abnormalities in sodium homeostasis are evident even in the early preascitic stage of cirrhosis. We aimed to investigate whether parameters of renal sodium handling...

Role of ANO4 in regulation of aldosterone secretion in the zona glomerulosa of the human adrenal gland.

Lancet (London, England)

Maniero C, Zhou J, Shaikh LH, Azizan EA, McFarlane I, Neogi S, Scudieri P, Galietta LJ, Brown MJ.
PMID: 26312884
Lancet. 2015 Feb 26;385:S62. doi: 10.1016/S0140-6736(15)60377-4.

BACKGROUND: Cell origin of aldosterone-producing adenomas, a major cause of hypertension, is unknown. A less common subtype of these adenomas, composed of cells resembling zona glomerulosa, have mutations in genes ATP1A1 and CACNA1D. To understand whether the adenomas originate...

Evaluation of clinical outcomes and costs based on prescribed dose level of renin-angiotensin-aldosterone system inhibitors.

The American journal of managed care

Epstein M, Alvarez PJ, Reaven NL, Funk SE, McGaughey KJ, Brenner MS, Benton W, Golestaneh L.
PMID: 27668789
Am J Manag Care. 2016 Aug;22(11):s311-s324.

No abstract available.

Evaluating the relationship of blood pressure, plasma angiotensin peptides and aldosterone with cognitive functions in patients with hypertension.

EXCLI journal

Sen S, Gürel N, Ufuktepe B, Özünal ZG, Büyüklü Ç, Üresin Y.
PMID: 28507470
EXCLI J. 2017 Mar 10;16:245-255. doi: 10.17179/excli2016-725. eCollection 2017.

Renin Angiotensin Aldosterone System (RAAS) plays an important role in the development of hypertension. On the other hand, hypertension is a well-known and independent risk factor for cognitive impairment. The aim of the present study was to evaluate the...

Patiromer induces rapid and sustained potassium lowering in patients with chronic kidney disease and hyperkalemia.

Kidney international

Bushinsky DA, Williams GH, Pitt B, Weir MR, Freeman MW, Garza D, Stasiv Y, Li E, Berman L, Bakris GL.
PMID: 26376130
Kidney Int. 2015 Dec;88(6):1427-1433. doi: 10.1038/ki.2015.270. Epub 2015 Sep 16.

Patients with chronic kidney disease (CKD) have a high risk of hyperkalemia, which increases mortality and can lead to renin-angiotensin-aldosterone system inhibitor (RAASi) dose reduction or discontinuation. Patiromer, a nonabsorbed potassium binder, has been shown to normalize serum potassium...

Cardio-renal protection through renin-angiotensin-aldosterone system inhibition: current knowledge and new perspectives.

European heart journal. Cardiovascular pharmacotherapy

Paolillo S, Perrone Filardi P.
PMID: 27533983
Eur Heart J Cardiovasc Pharmacother. 2015 Apr;1(2):132-3. doi: 10.1093/ehjcvp/pvv008. Epub 2015 Feb 24.

No abstract available.

The Challenges of Arterial Hypertension.

Frontiers in cardiovascular medicine

Rossi GP.
PMID: 26664874
Front Cardiovasc Med. 2015 Feb 03;2:2. doi: 10.3389/fcvm.2015.00002. eCollection 2015.

No abstract available.

[First Experience of Clinical Application of LCZ696 an AT1-angiotensin Receptors and Neprilysin Inhibitor in Patients With Chronic Heart Failure and Reduced Ejection Fraction].

Kardiologiia

Kobalava ZD, Pavlikova EP, Averkov OA, Merai I, Babaeva LA, Amirbegishvili IA, Kotovskaya YV, Moiseev VS.
PMID: 28294911
Kardiologiia. 2015 Jul;55(7):14-25.

Simultaneous inhibition of the renin-angiotensin-aldosterone system and the system of degradation of natriuretic peptides can potentially provide unique therapeutic effects in patients with chronic heart failure (CHF) with reduced ejection fraction (EF). Aim of this study was to assess...

Aldosterone predicts major adverse cardiovascular events in patients with acute myocardial infarction.

Heart Asia

Yuyun MF, Jutla SK, Quinn PA, Ng LL.
PMID: 27326041
Heart Asia. 2012 Aug 24;4(1):102-7. doi: 10.1136/heartasia-2012-010129. eCollection 2012.

OBJECTIVE: Aldosterone is associated with increased mortality in chronic heart failure patients and correlates with adverse outcomes after an acute myocardial infarction (AMI) in smaller cohorts. We evaluated the prognostic significance of plasma aldosterone in a large cohort of...

RETRACTED: Relationship Between Aldosterone Synthase CYP1A1 MspI Gene Polymorphism and Prostate Cancer Risk.

Technology in cancer research & treatment

Ou C, Zhao Y, Liu JH, Zhu B, Li PZ, Zhao HL.
PMID: 26763619
Technol Cancer Res Treat. 2017 Feb;16(1):NP6-NP11. doi: 10.1177/1533034615625519. Epub 2016 Jun 22.

No abstract available.

Showing 1 to 12 of 2536 entries