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Showing 1 to 12 of 35546 entries
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High ferritin and low transferrin saturation are associated with pre-diabetes among a national representative sample of U.S. adults.

Clinical nutrition (Edinburgh, Scotland)

Cheung CL, Cheung TT, Lam KS, Cheung BM.
PMID: 23312547
Clin Nutr. 2013 Dec;32(6):1055-60. doi: 10.1016/j.clnu.2012.11.024. Epub 2012 Dec 28.

BACKGROUND & AIMS: Iron overload is known to cause diabetes. However, the underlying mechanism is poorly understood. We therefore studied the association of different markers of iron metabolism, namely ferritin, erythrocyte protoporphyrin and transferrin saturation (TSAT, as defined by...

Hirmi Valley liver disease: a disease associated with exposure to pyrrolizidine alkaloids and DDT.

Journal of hepatology

Robinson O, Want E, Coen M, Kennedy R, van den Bosch C, Gebrehawaria Y, Kudo H, Sadiq F, Goldin RD, Hauser ML, Fenwick A, Toledano MB, Thursz MR.
PMID: 23973933
J Hepatol. 2014 Jan;60(1):96-102. doi: 10.1016/j.jhep.2013.07.039. Epub 2013 Aug 20.

BACKGROUND & AIMS: Hirmi Valley liver disease was first reported in 2001 in Tigray, Ethiopia. 591 cases, including 228 deaths, were reported up to December 2009. The pyrrolizidine alkaloid acetyllycopsamine was detected in stored grain and residents reported adding...

A novel mutation of the SLC25A13 gene in a Chinese patient with citrin deficiency detected by target next-generation sequencing.

Gene

Liu G, Wei X, Chen R, Zhou H, Li X, Sun Y, Xie S, Zhu Q, Qu N, Yang G, Chu Y, Wu H, Lan Z, Wang J, Yang Y, Yi X.
PMID: 24161253
Gene. 2014 Jan 10;533(2):547-53. doi: 10.1016/j.gene.2013.10.021. Epub 2013 Oct 23.

Type II citrullinaemia, also known as citrin deficiency, is an autosomal recessive metabolic disorder, which is caused by pathogenic mutations in the SLC25A13 gene on chromosome 7q21.3. One of the clinical manifestations of type II citrullinaemia is neonatal intrahepatic...

Hepatitis E virus seroprevalence and risk factors for individuals in working contact with animals.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology

Chaussade H, Rigaud E, Allix A, Carpentier A, Touzé A, Delzescaux D, Choutet P, Garcia-Bonnet N, Coursaget P.
PMID: 24084601
J Clin Virol. 2013 Nov;58(3):504-8. doi: 10.1016/j.jcv.2013.08.030. Epub 2013 Sep 12.

BACKGROUND: In industrial countries genotypes 3 and 4 of HEV are detected in swine, wild boar, deer and rabbits, and they are associated with autochthonous infections suggesting the existence of zoonotic HEV infections, compatible with the putative involvement of...

Anti-fibrosis and anti-cirrhosis effects of Rhizoma paridis saponins on diethylnitrosamine induced rats.

Journal of ethnopharmacology

Man S, Fan W, Gao W, Li Y, Wang Y, Liu Z, Li H.
PMID: 24212073
J Ethnopharmacol. 2014;151(1):407-12. doi: 10.1016/j.jep.2013.10.051. Epub 2013 Nov 07.

ETHNOPHARMACOLOGICAL RELEVANCE: Paris polyphylla var. yunnanensis as a traditional Chinese medicine has been used in the treatment of liver disease for thousands of years. Rhizoma paridis saponins (RPS), as the main active components of Paris polyphylla, have been used...

GPR120 on Kupffer cells mediates hepatoprotective effects of ω3-fatty acids.

Journal of hepatology

Raptis DA, Limani P, Jang JH, Ungethüm U, Tschuor C, Graf R, Humar B, Clavien PA.
PMID: 24262133
J Hepatol. 2014 Mar;60(3):625-32. doi: 10.1016/j.jhep.2013.11.006. Epub 2013 Nov 18.

BACKGROUND & AIMS: Many of the beneficial effects of ω3-fatty acids (ω3FAs) are being attributed to their anti-inflammatory properties. In animal models, ω3FAs also protect from hepatic ischemia reperfusion injury (IRI), a significant cause of complications following liver surgery....

Serum Basal Paraoxonase 1 Activity as an Additional Liver Function Test for the Evaluation of Patients with Chronic Hepatitis.

Journal of clinical and diagnostic research : JCDR

Pyati AK, Halappa CK, Pyati SA, Nagaraj, Wali V.
PMID: 26674516
J Clin Diagn Res. 2015 Nov;9(11):BC12-5. doi: 10.7860/JCDR/2015/15917.6850. Epub 2015 Nov 01.

BACKGROUND: The diagnostic accuracy of currently available standard panel of liver function tests is not satisfactory for the reliable diagnosis of chronic liver disorders. Earlier studies have reported that serum basal paraoxonase 1 (PON1) activity measurement may add a...

Infection should be an essential element of sepsis and the superiority of the newest sepsis definition.

The American journal of emergency medicine

Zhou X, Ye Y, Li J, Tang G.
PMID: 28209391
Am J Emerg Med. 2017 May;35(5):797-798. doi: 10.1016/j.ajem.2017.02.019. Epub 2017 Feb 09.

No abstract available.

Incidence and causes of mildly to moderately elevated aminotransferase in Japanese patients with type 2 diabetes.

Diabetology international

Chang CH, Sakaguchi M.
PMID: 31938683
Diabetol Int. 2019 Aug 14;11(1):57-66. doi: 10.1007/s13340-019-00405-w. eCollection 2020 Jan.

OBJECTIVES: To identify the association of type 2 diabetes (T2DM) and liver disease with elevated ALT and factors associated with increased ALT in patients with and without T2DM.DESIGN AND SETTING: We performed a retrospective study in adults with ≥...

The fat mass, estimated glomerular filtration rate, and chronic inflammation in type 2 diabetic patients.

Journal of clinical laboratory analysis

Šálek T, Adamíková A, Ponížil P.
PMID: 32045056
J Clin Lab Anal. 2020 Jun;34(6):e23229. doi: 10.1002/jcla.23229. Epub 2020 Feb 11.

BACKGROUND: The aim of the study was to analyze the degree of obesity and its associations with age, gender, inflammation, an estimated glomerular filtration rate (eGFR), and liver function in type 2 diabetes mellitus (T2DM) patients.METHODS: A total of...

Gas chromatographic-mass spectrometric analysis of sunscreens and their effects on mice liver and kidney enzyme function.

Clinical, cosmetic and investigational dermatology

Al-Eitan LN, Aljamal HA, Alkhatib RQ.
PMID: 30643445
Clin Cosmet Investig Dermatol. 2018 Dec 31;12:11-21. doi: 10.2147/CCID.S190359. eCollection 2019.

BACKGROUND: Sunscreens are one of the most widely used products among cosmetics and personal care products. Recent studies have shown that some of sunscreen formulations may contain toxic, carcinogenic, or even nonallowed chemicals that may affect skin, cells, and...

Utility of ALT Concentration in Men and Women with Nonalcoholic Fatty Liver Disease: Cohort Study.

Journal of clinical medicine

Sung KC, Lee MY, Lee JY, Lee SH, Kim SH, Kim SH.
PMID: 30987010
J Clin Med. 2019 Apr 02;8(4). doi: 10.3390/jcm8040445.

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of elevated alanine aminotransferase (ALT), but the clinical utility of ALT in detecting and following individuals with NAFLD remains unclear. We conducted a retrospective analysis of 30,988 men and...

Showing 1 to 12 of 35546 entries