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Showing 1 to 6 of 6 entries
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Extracellular Matrix in Heart Failure: Role of ADAMTS5 in Proteoglycan Remodeling.

Circulation

Barallobre-Barreiro J, Radovits T, Fava M, Mayr U, Lin WY, Ermolaeva E, Martínez-López D, Lindberg EL, Duregotti E, Daróczi L, Hasman M, Schmidt LE, Singh B, Lu R, Baig F, Siedlar AM, Cuello F, Catibog N, Theofilatos K, Shah AM, Crespo-Leiro MG, Doménech N, Hübner N, Merkely B, Mayr M.
PMID: 34806902
Circulation. 2021 Dec 21;144(25):2021-2034. doi: 10.1161/CIRCULATIONAHA.121.055732. Epub 2021 Nov 22.

BACKGROUND: Remodeling of the extracellular matrix (ECM) is a hallmark of heart failure (HF). Our previous analysis of the secretome of murine cardiac fibroblasts returned ADAMTS5 (a disintegrin and metalloproteinase with thrombospondin motifs 5) as one of the most...

Extracellular Matrix in Heart Failure: Role of ADAMTS5 in Proteoglycan Remodeling.

Circulation

Barallobre-Barreiro J, Radovits T, Fava M, Mayr U, Lin WY, Ermolaeva E, Martínez-López D, Lindberg EL, Duregotti E, Daróczi L, Hasman M, Schmidt LE, Singh B, Lu R, Baig F, Siedlar AM, Cuello F, Catibog N, Theofilatos K, Shah AM, Crespo-Leiro MG, Doménech N, Hübner N, Merkely B, Mayr M.
PMID: 34806902
Circulation. 2021 Dec 21;144(25):2021-2034. doi: 10.1161/CIRCULATIONAHA.121.055732. Epub 2021 Nov 22.

BACKGROUND: Remodeling of the extracellular matrix (ECM) is a hallmark of heart failure (HF). Our previous analysis of the secretome of murine cardiac fibroblasts returned ADAMTS5 (a disintegrin and metalloproteinase with thrombospondin motifs 5) as one of the most...

Beta3-adrenoceptor agonists: possible role in the treatment of overactive bladder.

Korean journal of urology

Igawa Y, Aizawa N, Homma Y.
PMID: 21221199
Korean J Urol. 2010 Dec;51(12):811-8. doi: 10.4111/kju.2010.51.12.811. Epub 2010 Dec 21.

In the present review article, we present an overview of beta-adrenoceptor (β-AR) subtype expression at the mRNA and receptor protein levels in the human detrusor, the in vitro and in vivo bladder function of the β3-AR, the in vivo...

Function and dysfunction of human sinoatrial node.

Korean circulation journal

Joung B, Chen PS.
PMID: 26023305
Korean Circ J. 2015 May;45(3):184-91. doi: 10.4070/kcj.2015.45.3.184. Epub 2015 May 27.

Sinoatrial node (SAN) automaticity is jointly regulated by a voltage (cyclic activation and deactivation of membrane ion channels) and Ca(2+) clocks (rhythmic spontaneous sarcoplasmic reticulum Ca(2+) release). Using optical mapping in Langendorff-perfused canine right atrium, we previously demonstrated that...

Extracellular Matrix in Heart Failure: Role of ADAMTS5 in Proteoglycan Remodeling.

Circulation

Barallobre-Barreiro J, Radovits T, Fava M, Mayr U, Lin WY, Ermolaeva E, Martínez-López D, Lindberg EL, Duregotti E, Daróczi L, Hasman M, Schmidt LE, Singh B, Lu R, Baig F, Siedlar AM, Cuello F, Catibog N, Theofilatos K, Shah AM, Crespo-Leiro MG, Doménech N, Hübner N, Merkely B, Mayr M.
PMID: 34806902
Circulation. 2021 Dec 21;144(25):2021-2034. doi: 10.1161/CIRCULATIONAHA.121.055732. Epub 2021 Nov 22.

BACKGROUND: Remodeling of the extracellular matrix (ECM) is a hallmark of heart failure (HF). Our previous analysis of the secretome of murine cardiac fibroblasts returned ADAMTS5 (a disintegrin and metalloproteinase with thrombospondin motifs 5) as one of the most...

Beta-adrenergic blocking drugs in breast cancer: a perspective review.

Therapeutic advances in medical oncology

Barron TI, Sharp L, Visvanathan K.
PMID: 22590485
Ther Adv Med Oncol. 2012 May;4(3):113-25. doi: 10.1177/1758834012439738.

The purpose of this review is to present the preclinical, epidemiological and clinical data relevant to the association between β-blockers and breast cancer progression. Preclinical studies have shown that β-adrenergic receptor (β-AR) signalling can inhibit multiple cellular processes involved...

Showing 1 to 6 of 6 entries