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Showing 1 to 12 of 1807 entries
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Biomarkers in kidney transplantation: From bench to bedside.

World journal of nephrology

Townamchai N, Eiam-Ong S.
PMID: 26558185
World J Nephrol. 2015 Nov 06;4(5):487-91. doi: 10.5527/wjn.v4.i5.487.

Immunosuppressive drug level monitoring and serum creatinine are widely used for kidney transplantation (KT) monitoring. Monitoring of drug level is not the direct measurement of the immune response while the rising of creatinine is too late for detection of...

Rg3 Improves Mitochondrial Function and the Expression of Key Genes Involved in Mitochondrial Biogenesis in C2C12 Myotubes.

Diabetes & metabolism journal

Kim MJ, Koo YD, Kim M, Lim S, Park YJ, Chung SS, Jang HC, Park KS.
PMID: 27535645
Diabetes Metab J. 2016 Oct;40(5):406-413. doi: 10.4093/dmj.2016.40.5.406. Epub 2016 Aug 12.

BACKGROUND: Panax ginseng has glucose-lowering effects, some of which are associated with the improvement in insulin resistance in skeletal muscle. Because mitochondria play a pivotal role in the insulin resistance of skeletal muscle, we investigated the effects of the...

Case of angina pectoris at rest and during effort due to coronary spasm and myocardial bridging.

World journal of cardiology

Teragawa H, Fujii Y, Ueda T, Murata D, Nomura S.
PMID: 26131343
World J Cardiol. 2015 Jun 26;7(6):367-72. doi: 10.4330/wjc.v7.i6.367.

We present a case of a 71-year-old male who had chest symptoms at rest and during effort. He had felt chest oppression during effort for 1 year, and his chest symptoms had recently worsened. One month before admission he...

Da-bu-yin-wan and qian-zheng-san to neuroprotect the mouse model of Parkinson's disease.

Evidence-based complementary and alternative medicine : eCAM

Gong XG, Sun HM, Zhang Y, Zhang SJ, Gao YS, Feng J, Hu JH, Gai C, Guo ZY, Xu H, Ma L.
PMID: 25610480
Evid Based Complement Alternat Med. 2014;2014:729195. doi: 10.1155/2014/729195. Epub 2014 Dec 24.

Da-Bu-Yin-Wan (DBYW) and Qian-Zheng-San (QZS), two classic traditional Chinese medicinal formulas, were clinically employed to treat Parkinson's disease (PD). Our previous studies demonstrated neuroprotective effects of them on mitochondrial function in PD mice induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). The purpose...

Selective Migration of Subpopulations of Bone Marrow Cells along an SDF-1α and ATP Gradient.

Bone marrow research

Laupheimer M, Skorska A, Große J, Tiedemann G, Steinhoff G, David R, Lux CA.
PMID: 25610653
Bone Marrow Res. 2014;2014:182645. doi: 10.1155/2014/182645. Epub 2014 Dec 31.

Both stem cell chemokine stromal cell-derived factor-1α (SDF-1α) and extracellular nucleotides such as adenosine triphosphate (ATP) are increased in ischemic myocardium. Since ATP has been reported to influence cell migration, we analysed the migratory response of bone marrow cells...

Bedaquiline for the treatment of multidrug-resistant tuberculosis: great promise or disappointment?.

Therapeutic advances in chronic disease

Field SK.
PMID: 26137207
Ther Adv Chronic Dis. 2015 Jul;6(4):170-84. doi: 10.1177/2040622315582325.

Acquired drug resistance by Mycobacterium tuberculosis (MTB) may result in treatment failure and death. Bedaquiline was recently approved for the treatment of multidrug-resistant tuberculosis (MDR-TB). This report examines the available data on this novel drug for the treatment of...

Induction of apoptosis by FFJ-5, a novel naphthoquinone compound, occurs via downregulation of PKM2 in A549 and HepG2 cells.

Oncology letters

Wei X, Li M, Ma M, Jia H, Zhang Y, Kang W, Wang T, Shi X.
PMID: 28356960
Oncol Lett. 2017 Feb;13(2):791-799. doi: 10.3892/ol.2016.5522. Epub 2016 Dec 20.

Pyruvate kinase isoenzyme M2 (PKM2) has previously been identified as a tumor biomarker and as a potential target for cancer therapy. In this study, F§FJ-5, a characterized naphthoquinone modifier of mollugin, was synthesized in order to investigate its anticancer...

AFP-producing acinar cell carcinoma treated by pancreaticoduodenectomy in a patient with a previous radical subtotal gastrectomy by gastric cancer.

Korean journal of hepato-biliary-pancreatic surgery

Kim CY, Lee SH, Jeon HM, Kim HK, Kang CM, Lee WJ.
PMID: 26155245
Korean J Hepatobiliary Pancreat Surg. 2014 Feb;18(1):33-7. doi: 10.14701/kjhbps.2014.18.1.33. Epub 2014 Feb 24.

We report a case of alpha-fetoprotein (AFP)-producing acinar cell carcinoma (ACC) of the pancreas. The tumor was diagnosed in a 72 yearold female after radical subtotal gastrectomy (Billroth I) due to early gastric cancer six months before. The initial...

Novel Aptasensor Platform Based on Ratiometric Surface-Enhanced Raman Spectroscopy.

Analytical chemistry

Wu Y, Xiao F, Wu Z, Yu R.
PMID: 28225598
Anal Chem. 2017 Mar 07;89(5):2852-2858. doi: 10.1021/acs.analchem.6b04010. Epub 2017 Feb 22.

A novel aptasensor platform has been developed for quantitative detection of adenosine triphosphate (ATP) based on a ratiometric surface-enhanced Raman scattering (SERS) strategy. The thiolated 3'-Rox-labeled complementary DNA (cDNA) is first immobilized on the gold nanoparticle (AuNP) surface and...

Cachexia: a problem of energetic inefficiency.

Journal of cachexia, sarcopenia and muscle

Argilés JM, Fontes-Oliveira CC, Toledo M, López-Soriano FJ, Busquets S.
PMID: 25118829
J Cachexia Sarcopenia Muscle. 2014 Dec;5(4):279-86. doi: 10.1007/s13539-014-0154-x. Epub 2014 Aug 15.

An alteration of energy balance is the immediate cause of the so-called cachexia. Although alterations of energy intake are often associated with cachexia, it has lately became clear that an increased energy expenditure is the main cause of wasting...

Hyperhomocysteinemia, Suppressed Immunity, and Altered Oxidative Metabolism Caused by Pathogenic Microbes in Atherosclerosis and Dementia.

Frontiers in aging neuroscience

McCully KS.
PMID: 29056905
Front Aging Neurosci. 2017 Oct 06;9:324. doi: 10.3389/fnagi.2017.00324. eCollection 2017.

Many pathogenic microorganisms have been demonstrated in atherosclerotic plaques and in cerebral plaques in dementia. Hyperhomocysteinemia, which is a risk factor for atherosclerosis and dementia, is caused by dysregulation of methionine metabolism secondary to deficiency of the allosteric regulator,...

Recent Update on Microbiological Monitoring of Gastrointestinal Endoscopes after High-Level Disinfection.

Clinical endoscopy

Shin SP, Kim WH.
PMID: 26473118
Clin Endosc. 2015 Sep;48(5):369-73. doi: 10.5946/ce.2015.48.5.369. Epub 2015 Sep 30.

Endoscopy-related infections are important contributors to nosocomial infections. Endoscope reprocessing according to standard guidelines ensures high-level disinfection and prevents endoscopy-related infections. Microbiological surveillance may help in monitoring the effectiveness of gastrointestinal endoscope disinfection. The process involves microbial cultures and...

Showing 1 to 12 of 1807 entries