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Showing 1 to 12 of 7888 entries
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Using caffeine and other adenosine receptor antagonists and agonists as therapeutic tools against neurodegenerative diseases: a review

Louis Stokes Alliances for Minority Participation AND Program Evaluation

Díaz-Ríos M.
GSID: QZwCBChNrw0J
M Rivera-Oliver, M Díaz-Ríos - Life sciences, 2014 - Elsevier

Caffeine is the most consumed pychostimulant in the world, and it is known to affect basic and fundamental human processes such as sleep, arousal, cognition and learning and memory. It works as a nonselective blocker of adenosine receptors (A1,...

Oxidative phosphorylation in Escherichia coli K 12. Mutations affecting magnesium ion- or calcium ion-stimulated adenosine triphosphatase

k-12

[No authors listed]
GSID: ZXGnEG0k9tgJ
JD Butlin, GB Cox, F Gibson - Biochemical Journal, 1971 - portlandpress.com

1. Two mutants of Escherichia coli K 12 were isolated which, although able to grow on glucose, are unable to grow with succinate or d-lactate as the sole source of carbon. 2. Genetic mapping of these mutants showed that...

Regulation of adenosine-activated GIRK channels by Gq-coupled receptors in mouse atrial myocytes

laboratory instruction

[No authors listed]
GSID: o9diU1QO6fYJ
H Cho - The Korean Journal of Physiology & Pharmacology, 2010 - synapse.koreamed.org

Adenosine (Ado) is an important mediator of the endogenous defense against ischemia-induced injury in the heart. The action of Ado is mediated by activation of G protein-gated …

Biomarkers in kidney transplantation: From bench to bedside.

World journal of nephrology

Townamchai N, Eiam-Ong S.
PMID: 26558185
World J Nephrol. 2015 Nov 06;4(5):487-91. doi: 10.5527/wjn.v4.i5.487.

Immunosuppressive drug level monitoring and serum creatinine are widely used for kidney transplantation (KT) monitoring. Monitoring of drug level is not the direct measurement of the immune response while the rising of creatinine is too late for detection of...

The case for performing pleural biopsies for the aetiological diagnosis of exudates. Yes.

Revista clinica espanola

Rodriguez-Panadero F.
PMID: 28410823
Rev Clin Esp (Barc). 2017 Oct;217(7):420-422. doi: 10.1016/j.rce.2017.02.015. Epub 2017 Apr 12.

Pleural biopsies are especially indicated in the following circumstances: a) inconclusive pleural fluid analysis and negative sputum study, if adenosine deaminase (ADA) levels are unavailable; b) suspected multi-resistant tuberculosis; c) a need for differentiating tuberculous pleurisy (if it progresses...

Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons.

Nature communications

Weinert T, Olieric N, Cheng R, Brünle S, James D, Ozerov D, Gashi D, Vera L, Marsh M, Jaeger K, Dworkowski F, Panepucci E, Basu S, Skopintsev P, Doré AS, Geng T, Cooke RM, Liang M, Prota AE, Panneels V, Nogly P, Ermler U, Schertler G, Hennig M, Steinmetz MO, Wang M, Standfuss J.
PMID: 28912485
Nat Commun. 2017 Sep 14;8(1):542. doi: 10.1038/s41467-017-00630-4.

Historically, room-temperature structure determination was succeeded by cryo-crystallography to mitigate radiation damage. Here, we demonstrate that serial millisecond crystallography at a synchrotron beamline equipped with high-viscosity injector and high frame-rate detector allows typical crystallographic experiments to be performed at...

Phosphodiesterase Inhibition and Regulation of Dopaminergic Frontal and Striatal Functioning: Clinical Implications.

The international journal of neuropsychopharmacology

Heckman PRA, van Duinen MA, Bollen EPP, Nishi A, Wennogle LP, Blokland A, Prickaerts J.
PMID: 27037577
Int J Neuropsychopharmacol. 2016 Apr 02;19(10). doi: 10.1093/ijnp/pyw030.

BACKGROUND: The fronto-striatal circuits are the common neurobiological basis for neuropsychiatric disorders, including schizophrenia, Parkinson's disease, Huntington's disease, attention deficit hyperactivity disorder, obsessive-compulsive disorder, and Tourette's syndrome. Fronto-striatal circuits consist of motor circuits, associative circuits, and limbic circuits. All...

Adenosine for the treatment of sustained sinus nodal reentrant tachycardia during general anesthesia.

Journal of anesthesia

Han DG, Rosenblatt MA, Reed AP.
PMID: 28921292
J Anesth. 1995 Jun;9(2):188-191. doi: 10.1007/BF02479855.

No abstract available.

Acitretin : A Review of its Pharmacology and Therapeutic Use.

Drugs

Pilkington T, Brogden RN.
PMID: 28421560
Drugs. 1992 Apr;43(4):597-627. doi: 10.2165/00003495-199243040-00010.

SYNOPSIS: Acitretin (etretin), a second generation monoaromatic retinoid for use in the treatment of severe psoriasis and other dermatoses, is the major active metabolite of etretinate and possesses a similar therapeutic index; i.e. a similar ratio of clinical efficacy...

Leukocyte Expression of Type 1 and Type 2 Purinergic Receptors and Pro-Inflammatory Cytokines during Total Sleep Deprivation and/or Sleep Extension in Healthy Subjects.

Frontiers in neuroscience

Chennaoui M, Arnal PJ, Drogou C, Leger D, Sauvet F, Gomez-Merino D.
PMID: 28512397
Front Neurosci. 2017 May 02;11:240. doi: 10.3389/fnins.2017.00240. eCollection 2017.

The purinergic type P1 (adenosine A

Rg3 Improves Mitochondrial Function and the Expression of Key Genes Involved in Mitochondrial Biogenesis in C2C12 Myotubes.

Diabetes & metabolism journal

Kim MJ, Koo YD, Kim M, Lim S, Park YJ, Chung SS, Jang HC, Park KS.
PMID: 27535645
Diabetes Metab J. 2016 Oct;40(5):406-413. doi: 10.4093/dmj.2016.40.5.406. Epub 2016 Aug 12.

BACKGROUND: Panax ginseng has glucose-lowering effects, some of which are associated with the improvement in insulin resistance in skeletal muscle. Because mitochondria play a pivotal role in the insulin resistance of skeletal muscle, we investigated the effects of the...

Early Intervention of Didang Decoction on MLCK Signaling Pathways in Vascular Endothelial Cells of Type 2 Diabetic Rats.

International journal of endocrinology

Ye S, Song Z, Li J, Li C, Yang J, Chang B.
PMID: 27703477
Int J Endocrinol. 2016;2016:6704851. doi: 10.1155/2016/6704851. Epub 2016 Sep 15.

In the study, type 2 diabetic rat model was established using streptozotocin (STZ) combined with a high-fat diet, and the rats were divided into control and diabetic groups. Diabetic groups were further divided into nonintervening, simvastatin, Didang Decoction (DDD)...

Showing 1 to 12 of 7888 entries