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Suicide genes: monitoring cells in patients with a safety switch.

Frontiers in pharmacology

Eissenberg LG, Rettig M, Dehdashti F, Piwnica-Worms D, DiPersio JF.
PMID: 25414668
Front Pharmacol. 2014 Nov 06;5:241. doi: 10.3389/fphar.2014.00241. eCollection 2014.

Clinical trials increasingly incorporate suicide genes either as direct lytic agents for tumors or as safety switches in therapies based on genetically modified cells. Suicide genes can also be used as non-invasive reporters to monitor the biological consequences of...

Showing 1 to 1 of 1 entries