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Similar articles for PMID: 1965400

Showing 1 to 12 of 96 entries
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Evidence against the adenosine-catecholamine antagonism in the canine heart in situ.


Schipke J, Heusch G, Thämer V.
PMID: 3449061
Arzneimittelforschung. 1987 Dec;37(12):1345-7.

Adenosine has been reported to attenuate the positive inotropic effects of catecholamines in isolated heart preparations of rodents. These results were not confirmed in anesthetized dogs during intracoronary infusion of isoprenaline. However, these experiments did not establish the effects...

Decreased flow reserve in "stunned" myocardium after a 10-min coronary occlusion.

The American journal of physiology

Triana JF, Bolli R.
PMID: 1887925
Am J Physiol. 1991 Sep;261(3):H793-804. doi: 10.1152/ajpheart.1991.261.3.H793.

The effect of brief reversible ischemia on coronary vascular function remains controversial. Studies using a 15-min coronary occlusion have reported an impairment of vasodilator reserve, whereas studies using shorter occlusions have not. To elucidate the relation between postischemic vascular...

Coronary pressure-flow, pressure-function, and function-myocardial oxygen consumption relations in postischaemic myocardium.

Cardiovascular research

Kawashima S, Satani A, Tsumoto S, Kondo T, Ikeoka K, Morita M, Iwasaki T.
PMID: 1747877
Cardiovasc Res. 1991 Oct;25(10):837-43. doi: 10.1093/cvr/25.10.837.

STUDY OBJECTIVE: The aim was to study coronary pressure-flow, pressure-myocardial wall motion and myocardial wall motion-myocardial oxygen consumption relations in postischaemic myocardium with prolonged myocardial dysfunction (stunned myocardium) in comparison with normal myocardium.DESIGN: Regional myocardial wall thickening was measured...

Sympathetic stimulation and norepinephrine infusion modulate extracellular potassium concentration during acute myocardial ischemia.

Circulation research

Warner MR, Kroeker TS, Zipes DP.
PMID: 1394871
Circ Res. 1992 Nov;71(5):1078-87. doi: 10.1161/01.res.71.5.1078.

The purpose of this study was to investigate whether sympathetic stimulation modulated the rise in extracellular K+ concentration ([K+]o) evoked by acute myocardial ischemia. In 35 alpha-chloralose-anesthetized dogs, we measured changes in [K+]o during acute myocardial ischemia in the...

Acute and chronic effects of transient myocardial ischemia on sympathetic nerve activity, density, and norepinephrine content.

Cardiovascular research

Dae MW, O'Connell JW, Botvinick EH, Chin MC.
PMID: 7585815
Cardiovasc Res. 1995 Aug;30(2):270-80.

OBJECTIVES: The sympathetic nervous system has profound influences on myocardial function, particularly during ischemia. There is controversy, however, as to whether myocardial ischemia results in damage to myocardial sympathetic nerves coursing through the ischemic territory. To further evaluate these...

Parenteral magnesium sulphate restores regional contractile function in the post-ischaemic canine myocardium.

Magnesium research

Mass H, Santoni F, Feliciano L, Santiago O, Albino D, De Leon N, Sifonte M.
PMID: 7786688
Magnes Res. 1994 Dec;7(3):255-66.

The effects of parenteral magnesium sulphate (MS) on the regional contractile response of stunned myocardium was examined in 45 pentobarbital anaesthetized dogs. The hearts were instrumented to measure left ventricular pressure (LVP), coronary flow velocity (CFV), mean arterial blood...

Controlled intermittent asystole cardiac therapy induced by pharmacologically potentiated vagus nerve stimulation in normal and hibernating myocardium.

The Annals of thoracic surgery

Ronson RS, Puskas JD, Thourani VH, Velez DA, Bufkin BL, Glass J, Guyton RA, Vinten-Johansen J.
PMID: 12822638
Ann Thorac Surg. 2003 Jun;75(6):1929-36. doi: 10.1016/s0003-4975(03)00115-2.

BACKGROUND: Pharmacologically potentiated electrical stimulation of the right vagus nerve achieves controlled intermittent asystole cardiac therapy. The present study examined pathophysiologic consequences of repetitive intermittent asystoles on contractile function, myocardial blood flow, and vagus nerve function and morphology.METHODS: Open-chest...

Blunted functional responses to pre- and postjunctional sympathetic stimulation in hibernating myocardium.

American journal of physiology. Heart and circulatory physiology

Ovchinnikov V, Suzuki G, Canty JM, Fallavollita JA.
PMID: 15923318
Am J Physiol Heart Circ Physiol. 2005 Oct;289(4):H1719-28. doi: 10.1152/ajpheart.00273.2005. Epub 2005 May 27.

Regional reductions in norepinephrine-tracer uptake are found in pigs with hibernating myocardium. Clinical studies would suggest that this is evidence for denervation; however, the functional responses to sympathetic stimulation have not been evaluated, and our previous studies with beta-adrenergic...

Mechanism of myocardial protection by isoflurane. Role of adenosine triphosphate-regulated potassium (KATP) channels.


Kersten JR, Schmeling TJ, Hettrick DA, Pagel PS, Gross GJ, Warltier DC.
PMID: 8873550
Anesthesiology. 1996 Oct;85(4):794-807; discussion 27A. doi: 10.1097/00000542-199610000-00015.
Free Article

BACKGROUND: The mechanism of the protective actions of volatile anesthetics in ischemic myocardium has not been clearly elucidated. The role of myocardial adenosine triphosphate-regulated potassium (KATP) channels in isoflurane-induced enhancement of recovery of regional contractile function after multiple brief...

Intracoronary amiloride prevents contractile dysfunction of postischemic "stunned" myocardium: role of hemodynamic alterations and inhibition of Na+/H+ exchange and L-type Ca2+ channels.

Journal of the American College of Cardiology

Smart SC, LoCurto A, el Schultz J, Sagar KB, Warltier DC.
PMID: 7594055
J Am Coll Cardiol. 1995 Nov 01;26(5):1365-73. doi: 10.1016/0735-1097(95)00326-6.
Free Article

OBJECTIVES: This study sought to establish the effect of amiloride on stunned myocardium and to determine the role of hemodynamic alterations and inhibition of sodium/proton (Na+/H+) exchange and L-type cytosolic calcium (Ca2+) channels.BACKGROUND: Amiloride is a nonspecific agent that...

Lack of modulation by dietary unsaturated fats on sympathetic neurotransmission in rat hearts.

The American journal of physiology

Du XJ, Dart AM, Riemersma RA.
PMID: 8214123
Am J Physiol. 1993 Sep;265(3):H886-92. doi: 10.1152/ajpheart.1993.265.3.H886.

We examined the effect of dietary polyunsaturated fatty acids (PUFA) on cardiac sympathetic neurotransmission. Rats were fed semisynthetic diets (18.5% fat wt/wt) high in saturated fatty acids (control diet), high in n-6 PUFA (corn oil), or enriched with n-3...

The effects of neuronal uptake blockade on the cardiac responses to sympathetic nerve stimulation and norepinephrine infusion in anesthetized dogs.

Journal of the autonomic nervous system

Masuda Y, Levy MN.
PMID: 6327795
J Auton Nerv Syst. 1984 Mar;10(1):1-17. doi: 10.1016/0165-1838(84)90063-8.

In anesthetized dogs, cocaine ( COC ) was administered intravenously in order to block the neuronal uptake of norepinephrine (NE) by the heart. COC had relatively little effect on the magnitudes of the inotropic and chronotropic responses to sympathetic...

Showing 1 to 12 of 96 entries